Keiko Yamakawa
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Explore the profile of Keiko Yamakawa including associated specialties, affiliations and a list of published articles.
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64
Citations
404
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Recent Articles
1.
Ye J, Suizu F, Yamakawa K, Mukai Y, Yoneyama H, Kondo J, et al.
Mol Ther Oncol
. 2024 May;
32(2):200812.
PMID: 38799652
The dense stroma is one cause of poor efficacy of T cell-mediated immunotherapy in pancreatic ductal adenocarcinoma (PDAC). Carbohydrate sulfotransferase 15 (CHST15) is a proteoglycan-synthetic enzyme responsible for remodeling tumor...
2.
Natsume K, Ye J, Mukai Y, Yamakawa K, Tanimoto M, Ito H, et al.
Anticancer Res
. 2024 Feb;
44(2):711-722.
PMID: 38307593
Background/aim: Immunohistochemical (IHC) staining has been routinely used to distinguish adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of the lungs; however, it is challenging to obtain an accurate diagnosis, especially...
3.
Ye J, Suizu F, Yamakawa K, Mukai Y, Kato M, Yoneyama H, et al.
Eur J Immunol
. 2023 May;
53(9):e2250160.
PMID: 37248998
Limited intratumoral T-cell infiltration in pancreatic ductal adenocarcinoma (PDAC) is an obstacle to immunotherapy, yet the efficient approach to enhance tumor-infiltrating T cells is not fully established. Here, we show...
4.
Matsuda Y, Ye J, Yamakawa K, Mukai Y, Azuma K, Wu L, et al.
J Natl Cancer Inst
. 2022 Dec;
115(2):208-218.
PMID: 36567450
Background: Telomere dysfunction has been reported to be directly involved in carcinogenesis owing to chromosomal instability and immortalization; however, the clinicopathological significance of telomeres remains controversial. We have shown that...
5.
Nishino T, Abe T, Kaneko M, Yokohira M, Yamakawa K, Imaida K, et al.
Biochem Biophys Res Commun
. 2022 Sep;
628:91-97.
PMID: 36084556
The adaptor protein GAREM has two subtypes. Each is involved in Erk activation signaling downstream of the cell growth factor receptor in cultured cells. Regarding their role in individual animals,...
6.
Yamakawa K, Mukai Y, Ye J, Muto-Ishizuka M, Ito M, Tanimoto M, et al.
Sci Rep
. 2022 Apr;
12(1):6143.
PMID: 35414715
Telomeres are tandem repeats of the TTAGGG sequence at chromosomal ends and afford protection against chromosomal instability. To investigate the contribution of telomere dysfunction in meningiomas, here we estimate the...
7.
Matsuda Y, Yamashita T, Ye J, Yasukawa M, Yamakawa K, Mukai Y, et al.
J Pathol
. 2022 Jan;
257(2):172-185.
PMID: 35094384
Recent evidence indicates that RNA-dependent RNA polymerase (RdRP) activity of human telomerase reverse transcriptase (hTERT) regulates expression of target genes and is directly involved in tumor formation in a telomere-independent...
8.
Kameyama A, Ye J, Shimomura A, Yokohira M, Nakano-Narusawa Y, Yamakawa K, et al.
Pancreatology
. 2021 Sep;
21(8):1506-1515.
PMID: 34563448
Background: The pathologic assessments of tumor response after neoadjuvant chemoradiotherapy (NACRT) are critical to improving the prognostic stratification for patients with pancreatic ductal adenocarcinoma (PDAC). Here we clarified the utility...
9.
Suemitsu Y, Ono Y, Mizukami Y, Ye J, Yamakawa K, Takamoto T, et al.
Front Oncol
. 2021 Sep;
11:725290.
PMID: 34513702
Background: Pancreatoblastoma is a rare malignant epithelial neoplasm of the pancreas that mainly occurs in children and involves abnormalities in the WNT/β-catenin pathway, such as mutation. However, the molecular abnormalities...
10.
Nakano-Narusawa Y, Yokohira M, Yamakawa K, Ye J, Tanimoto M, Wu L, et al.
Cancers (Basel)
. 2021 Jul;
13(12).
PMID: 34200786
Lung cancer remains the leading cause of cancer-related deaths, with an estimated 1.76 million deaths reported in 2018. Numerous studies have focused on the prevention and treatment of lung cancer...