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Keiko Hoshi

Explore the profile of Keiko Hoshi including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 147
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Recent Articles
1.
Katagiri N, Chida S, Abe K, Nojima H, Kitabatake M, Hoshi K, et al.
Brain Res . 2010 Feb; 1321:133-42. PMID: 20114039
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is well known as an exogenous dopaminergic neurotoxin that induces Parkinson's disease-like symptoms. In addition, 1,2,3,4-tetrahydroisoquinoline (TIQ) derivatives have been investigated as endogenous MPTP mimetic compounds that structurally...
2.
Utsunomiya I, Tanabe S, Terashi T, Ikeno S, Miyatake T, Hoshi K, et al.
J Neurochem . 2009 Dec; 112(4):913-23. PMID: 19968754
The Kv1.4 potassium channel is reported to exhibit higher cell surface expression than the Kv1.1 potassium channel when expressed as a homomer in cell lines. Kv1.4 also shows highly efficient...
3.
Futaki N, Harada M, Sugimoto M, Hashimoto Y, Honma Y, Arai I, et al.
J Pharm Pharmacol . 2009 May; 61(5):607-14. PMID: 19405999
Objectives: Lornoxicam is a non-selective cyclooxygenase inhibitor that exhibits strong analgesic and anti-inflammatory effects but a weak antipyretic effect in rat models. Our aim was to investigate the mechanism of...
4.
Nakatani Y, Murata M, Shibata K, Nagaoka T, Utsunomiya I, Usuki S, et al.
Exp Neurol . 2009 Mar; 219(1):74-80. PMID: 19306874
Miller-Fisher syndrome (MFS), which is known to be associated with anti-GQ1b antibodies and to cause ataxia, is a variant of an acute inflammatory neuropathy. However, the pathogenic role of anti-GQ1b...
5.
Murata M, Katagiri N, Ishida K, Abe K, Ishikawa M, Utsunomiya I, et al.
Brain Res . 2009 Mar; 1269:40-6. PMID: 19285043
It is known that psychostimulants stimulate dopamine transmission in the nucleus accumbens. In the present study, we examined the effects of systemically administered beta-phenylethylamine (beta-PEA), a psychomotor-stimulating trace amine, on...
6.
Toshima H, Sugihara H, Hamano H, Sato M, Yamamoto M, Yamazaki S, et al.
Platelets . 2008 Jun; 19(4):293-9. PMID: 18569865
Platelet aggregometry by the laser light scattering (LS) method is sufficiently sensitive to detect small platelet aggregates that form spontaneously in vitro in the absence of agonists. Platelet aggregation without...
7.
Nakatani Y, Hotta S, Utsunomiya I, Tanaka K, Hoshi K, Ariga T, et al.
Neurochem Res . 2008 May; 34(1):149-57. PMID: 18478327
To investigate the pathophysiological mechanisms of immune-mediated peripheral neuropathies, we studied the effects of sera from patients with Guillain-Barré syndrome (GBS) on the Cav2.1 voltage-dependent calcium channel (VDCC) current in...
8.
Utsunomiya I, Yoshihashi E, Tanabe S, Nakatani Y, Ikejima H, Miyatake T, et al.
Exp Neurol . 2007 Dec; 210(1):51-8. PMID: 18053989
We investigated the expression and localization of Kv1 channels in dorsal spinal roots (DRs) and ventral spinal roots (VRs) in rats. Among Kv1.1-1.6 tested by RT-PCR, mRNAs of Kv1.1, 1.2,...
9.
Fujita T, Ikejima H, Yamagata N, Kudo Y, Hoshi K
Biol Pharm Bull . 2007 Nov; 30(11):2027-30. PMID: 17978470
Human parvovirus B19 is a clinically important pathogen in both children and adults. In adults, it frequently causes acute and chronic arthritis, which may be related to persistent infection. The...
10.
Hara M, Abe T, Sugawara S, Mizushima Y, Hoshi K, Irimajiri S, et al.
Mod Rheumatol . 2007 Feb; 17(1):10-6. PMID: 17278016
We conducted a 52-week clinical study of iguratimod in 394 Japanese patients with rheumatoid arthritis to evaluate the long-term safety of the drug. Iguratimod was administered orally at a daily...