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Keighley N Reisenauer

Explore the profile of Keighley N Reisenauer including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Reisenauer K, Aroujo J, Tao Y, Ranganathan S, Romo D, Taube J
Nat Prod Rep . 2023 Apr; 40(8):1432-1456. PMID: 37103550
Covering: 1995 to 2022Tumors possess both genetic and phenotypic heterogeneity leading to the survival of subpopulations post-treatment. The term cancer stem cells (CSCs) describes a subpopulation that is resistant to...
2.
Reisenauer K, Tao Y, Das P, Song S, Svatek H, Patel S, et al.
Sci Rep . 2021 May; 11(1):10652. PMID: 34017048
The epithelial-mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells with...
3.
Tao Y, Reisenauer K, Masi M, Evidente A, Taube J, Romo D
Org Lett . 2020 Oct; 22(21):8307-8312. PMID: 33034457
Pharmacophore-directed retrosynthesis applied to ophiobolin A led to bicyclic derivatives that were synthesized and display anticancer activity. Key features of the ultimate defensive synthetic strategy include a Michael addition/facially selective...
4.
Taube J, Sphyris N, Johnson K, Reisenauer K, Nesbit T, Joseph R, et al.
Oncotarget . 2017 Oct; 8(39):65548-65565. PMID: 29029452
The deposition of the activating H3K4me3 and repressive H3K27me3 histone modifications within the same promoter, forming a so-called bivalent domain, maintains gene expression in a repressed but transcription-ready state. We...