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Ke-Yu Deng

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Articles 56
Citations 1084
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Recent Articles
1.
Gu H, Wang L, Zhang Y, Zhuo Y, Zhang Z, Wei X, et al.
Cell Mol Biol Lett . 2025 Feb; 30(1):21. PMID: 39972244
Background: Cyclophosphamide (CTX) is the first-line medication for the treatment of breast cancer, although it potentially leads to severe ovarian dysfunction and even premature ovarian failure (POF). However, the mechanism...
2.
Hu M, Guan X, Wang L, Xu H, Ke S, Yuan Q, et al.
Cell Mol Life Sci . 2024 Dec; 82(1):30. PMID: 39725783
Idiopathic pulmonary fibrosis (IPF) is a prevalent interstitial lung disease with high mortality. CD38 is a main enzyme for intracellular nicotinamide adenine dinucleotide (NAD) degradation in mammals. It has been...
3.
Huang Q, Zhuo Y, Duan Z, Long Y, Wang J, Zhang Z, et al.
Bone Joint Res . 2024 Dec; 13(12):763-777. PMID: 39662502
Aims: Mesenchymal stem cells (MSCs) are usually cultured in a normoxic atmosphere (21%) in vitro, while the oxygen concentrations in human tissues and organs are 1% to 10% when the...
4.
Lin C, He M, An M, Zhao Q, Zhang Z, Deng K, et al.
Small . 2024 Oct; 20(51):e2403313. PMID: 39377344
Hepatic ischemia-reperfusion injury (IRI) is a severe complication that occurs in the process of liver transplantation, hepatectomy, and other end-stage liver disease surgery, often resulting in the failure of surgery...
5.
Wang L, Li Q, Le Zhao J, Wen K, Zhang Y, Zhao Q, et al.
Biochem Cell Biol . 2024 Aug; 103():1-12. PMID: 39116458
Diabetic nephropathy (DN) is one of the most common complications of diabetes. Our previous study showed that CD38 knockout (CD38KO) mice had protective effects on many diseases. However, the roles...
6.
Pang Y, Hu H, Xu K, Cao T, Wang Z, Nie J, et al.
Invest Ophthalmol Vis Sci . 2024 May; 65(5):36. PMID: 38776115
Purpose: The purpose of this study was to investigate the protective effect of CD38 deletion on retinal ganglion cells (RGCs) in a mouse retinal ischemia/reperfusion (I/R) model and an optic...
7.
Yu Z, Wang Y, Wang X, Gong L, Tan H, Jiang M, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673941
Abdominal aortic aneurysm (AAA) is a serious vascular disease which is associated with vascular remodeling. CD38 is a main NAD-consuming enzyme in mammals, and our previous results showed that CD38...
8.
Huang Q, Long Y, Wang J, Wu J, Tang W, Wang X, et al.
Int Immunopharmacol . 2024 Feb; 129:111660. PMID: 38350357
Background: Human amniotic mesenchymal stem cells (hAMSCs) derived from amniotic membrane have multilineage differentiation, immunosuppressive, and anti-inflammation which makes them suitable for the treatment of various diseases. Objective: This study...
9.
He J, Tang M, Liu L, Kong C, Chen W, Wang L, et al.
Cell Mol Gastroenterol Hepatol . 2024 Feb; 17(6):965-981. PMID: 38342302
Background & Aims: Hepatic ischemia-reperfusion injury (HIRI) often occurs in liver surgery, such as partial hepatectomy and liver transplantation, in which myeloid macrophage-mediated inflammation plays a critical role. Cell division...
10.
Wang L, Li Q, Wen K, Zhao Q, Zhang Y, Zhao J, et al.
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958991
Diabetic cardiomyopathy is one of the diabetes mellitus-induced cardiovascular complications that can result in heart failure in severe cases, which is characterized by cardiomyocyte apoptosis, local inflammation, oxidative stress, and...