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Kazumi Yokomizo

Explore the profile of Kazumi Yokomizo including associated specialties, affiliations and a list of published articles. Areas
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Articles 49
Citations 250
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Recent Articles
1.
Misuda N, Watanabe M, Nishikawa H, Yasuda S, Miyashita H, Yokomizo K, et al.
J Nat Med . 2024 Dec; 79(2):341-356. PMID: 39729184
Ipomoea alba L. (Convolvulaceae) is an annual vine native to tropical America that is cultivated primarily for ornamental purposes. Its seeds are used in traditional medicine as a laxative, and...
2.
Zhou J, Kinno S, Kaihara K, Sawai M, Ishida T, Takechi S, et al.
Nutrients . 2024 Jun; 16(11). PMID: 38892635
Dendritic cells (DCs) can initiate immune response through the presenting antigens to naïve T lymphocytes. Esculeoside A (EsA), a spirosolane glycoside, is reported as a major component in the ripe...
3.
Ono M, Tenmaya D, Tarumi M, Satou S, Tsuji K, Nishikawa H, et al.
J Nat Med . 2024 Mar; 78(3):525-536. PMID: 38457082
Ipomoea muricata (L.) Jacq. seeds (Convolvulaceae) are used as a traditional laxative and carminative medicine. Muricatins XIV (1), XV (2), XVI (3), and XVII (4), were isolated from I. muricata...
4.
Gao S, Yang K, Nohara T, Ikeda T, Zhou J, Yokomizo K, et al.
Antioxidants (Basel) . 2023 Apr; 12(4). PMID: 37107245
This study aimed to investigate the pharmacological activities of garlicnin B1, a cyclic sulfide compound found abundantly in garlic and structurally similar to onionin A1, which has been shown to...
5.
Islam R, Kotalik K, Subr V, Gao S, Zhou J, Yokomizo K, et al.
Nanomedicine . 2022 Dec; 48:102636. PMID: 36549553
In this study, we developed a nanoformulation of 5-aminolevulinic acid (5-ALA) for tumor-targeted photodynamic therapy, in which 5-ALA was conjugated with a biocompatible polymer N-(2-hydroxypropyl)methacrylamide (HPMA) through the hydrazone bond,...
6.
Zhou J, Yamada R, Huruiti E, Kitahara N, Nakamura H, Fang J, et al.
Nutrients . 2022 May; 14(10). PMID: 35631161
We report that esculeoside A (EsA), a glycoside and a major component in ripe tomato fruit, ameliorated experimental dermatitis in mice. However, the underlying immunologic molecular mechanisms are unknown. The...
7.
Subr V, Pola R, Gao S, Islam R, Hirata T, Miyake D, et al.
J Pers Med . 2022 May; 12(5). PMID: 35629120
Biodegradable nanomedicines are widely studied as candidates for the effective treatment of various cancerous diseases. Here, we present the design, synthesis and evaluation of biodegradable polymer-based nanomedicines tailored for tumor-associated...
8.
Zhou J, Kitahara N, Nakamura H, Ono T, Karashima R, Fang J, et al.
J Pers Med . 2022 Apr; 12(4). PMID: 35455695
(1) Background: A naturally occurring glycoside, esculeoside B (EsB), has been identified as a major component in juice or canned tomato. We reported how EsB ameliorated mice experimental atopic dermatitis...
9.
Zhou J, Tokutomi N, Satou Y, Yasuda S, Kinoshita H, Nohara T, et al.
BMC Complement Med Ther . 2022 Mar; 22(1):82. PMID: 35317794
Background: Pharbitidis Semen (the seeds of Pharbitis nil), traditionally used as a purgative in Japan, China and Korea, contains a resin glycoside fraction named pharbitin, which is known as a...
10.
Fang J, Islam R, Gao S, Zhang C, Kunisaki R, Sakaguchi S, et al.
J Pers Med . 2021 Dec; 11(12). PMID: 34945812
Heme oxygenase (HO-1) plays an important role in cellular protection against various stresses. The induction of HO-1 is an effective strategy for reactive oxygen species-related diseases, inflammatory diseases, as well...