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Kazumi Yamauchi

Explore the profile of Kazumi Yamauchi including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 217
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Recent Articles
1.
Yamauchi K, Tsutsumi Y, Kobayashi T, Komura J
Radiat Prot Dosimetry . 2024 Nov; 200(16-18):1594-1597. PMID: 39540528
ApcMin/+ mouse was a model mouse for human familial adenomatous polyposis, and irradiation at an early age increases tumors in the small and large intestine. To study the effects of...
2.
Uemura I, Takahashi-Suzuki N, Kuroda S, Kumagai K, Tsutsumi Y, Anderson D, et al.
Radiat Prot Dosimetry . 2024 Nov; 200(16-18):1620-1624. PMID: 39540488
This study investigated the effects of chronic low-dose-rate radiation exposure on gene expression related to immunological defense mechanisms and epigenetic regulation in the testis of male mice. The study found...
3.
Ohno M, Takano N, Hidaka K, Sasaki F, Yamauchi K, Aoki Y, et al.
Genome Res . 2024 Jan; 34(1):47-56. PMID: 38290979
Oxidative stress-induced DNA damage and its repair systems are related to cancer etiology; however, the molecular basis triggering tumorigenesis is not well understood. Here, we aimed to explore the causal...
4.
Yamauchi K, Ono T, Ayabe Y, Hisamatsu S, Yoneya M, Tsutsumi Y, et al.
Radiat Res . 2019 Aug; 192(4):451-455. PMID: 31390311
Calorie restriction is known to influence several physiological processes and to alleviate the late effects of radiation exposure such as neoplasm induction and life shortening. However, earlier related studies were...
5.
Nakayama T, Sawai T, Masuda I, Kaneko S, Yamauchi K, Blyth B, et al.
Environ Mol Mutagen . 2017 Sep; 58(8):592-606. PMID: 28921690
DNA mutations play a crucial role in the origins of cancer, and the clonal expansion of mutant cells is one of the fundamental steps in multistage carcinogenesis. In this study,...
6.
Isoda T, Nakatsu Y, Yamauchi K, Piao J, Yao T, Honda H, et al.
Int J Biol Sci . 2014 Aug; 10(8):940-7. PMID: 25170306
MUTYH is a DNA glycosylase that excises adenine paired with 8-oxoguanine to prevent mutagenesis in mammals. Biallelic germline mutations of MUTYH have been found in patients predisposed to a recessive...
7.
Shang Y, Kakinuma S, Yamauchi K, Morioka T, Kokubo T, Tani S, et al.
Int J Cancer . 2014 Feb; 135(5):1038-47. PMID: 24482070
Children are especially sensitive to ionizing radiation and chemical carcinogens, and limiting their cancer risk is of great public concern. Calorie restriction (CR) is a potent intervention for suppressing cancer....
8.
Kakinuma S, Nishimura M, Amasaki Y, Takada M, Yamauchi K, Sudo S, et al.
Mutat Res . 2012 Jun; 737(1-2):43-50. PMID: 22706209
Ionizing radiation is a well-known carcinogen, but its potency may be influenced by other environmental carcinogens, which is of practical importance in the assessment of risk. Data are scarce, however,...
9.
He D, Uehara Y, Furuya M, Ikehata H, Komura J, Yamauchi K, et al.
Mech Ageing Dev . 2011 Feb; 132(3):117-22. PMID: 21300080
To understand the effect of calorie restriction on genome maintenance systems, the age-dependent accumulation of mutations in animals maintained on high and low calorie diets was examined using lacZ-transgenic mice....
10.
Ishida Y, Takabatake T, Kakinuma S, Doi K, Yamauchi K, Kaminishi M, et al.
Carcinogenesis . 2010 Jul; 31(9):1694-701. PMID: 20616149
Accurate cancer risk assessment of low-dose radiation poses many challenges that are partly due to the inability to distinguish radiation-induced tumors from spontaneous ones. To elucidate characteristic features of radiation-induced...