Kazuhiro Hashiguchi
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Explore the profile of Kazuhiro Hashiguchi including associated specialties, affiliations and a list of published articles.
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16
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76
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Recent Articles
1.
Hashiguchi K, Okubo K, Inoue Y, Numaguchi H, Tanaka K, Oshima N, et al.
Allergy Rhinol (Providence)
. 2018 Jul;
9:2152656718783599.
PMID: 30027002
Background: This study evaluated the efficacy of montelukast in reducing seasonal allergic rhinitis symptoms in Japanese children with Japanese cedar (JC) pollinosis induced in an artificial exposure chamber (OHIO Chamber)....
2.
Kanzaki S, Hashiguchi K, Wakabayashi K, Suematsu K, Okubo K
J Drug Assess
. 2016 Oct;
5(1):15-23.
PMID: 27785375
To determine the efficacy of the antihistamine bepotastine on treating nasal symptoms in patients with Japanese cedar and cypress pollinosis, based on two previous studies that looked at bepotastine OD's...
3.
Hosoya K, Masuno S, Hashiguchi K, Okubo K
J Drug Assess
. 2016 Aug;
3(1):51-9.
PMID: 27536454
Objective: This double-blind, placebo-controlled comparative study was designed to investigate whether pranlukast dry syrup, a leukotriene receptor antagonist, has a protective effect against priming, controlled pollen exposure, and natural pollen...
4.
Hashiguchi K, Kanzaki S, Wakabayashi K, Tanaka N, Kawashima K, Suematsu K, et al.
J Drug Assess
. 2016 Aug;
2(1):94-105.
PMID: 27536443
Objective: This study investigated the clinical efficacy of a combination therapy of levocetirizine (LCTZ) and fluticasone furoate nasal spray (FFNS), compared with LCTZ monotherapy, for the suppression of seasonal allergic...
5.
Endo S, Gotoh M, Okubo K, Hashiguchi K, Suzuki H, Masuyama K
J Drug Assess
. 2016 Aug;
1(1):48-54.
PMID: 27536428
Objective: In practical guidelines for management of allergic rhinitis in Japan, pranlukast is a leukotriene receptor antagonist recommended for the treatment of pollinosis. However, the effect of pranlukast on nasal...
6.
Hashiguchi K, Okubo K, Wakabayashi K, Tanaka N, Watada Y, Suematsu K, et al.
J Drug Assess
. 2016 Aug;
1(1):40-7.
PMID: 27536427
Objective: The study objective was to investigate the prophylactic efficacy of montelukast (MLK) 10 mg in suppressing seasonal allergic rhinitis (SAR) symptoms induced by Japanese cedar (JC) pollen and to...
7.
Hashiguchi K, Wakabayashi K, Togawa M, Saito A, Okubo K
Allergol Int
. 2016 Aug;
66(1):123-131.
PMID: 27475625
Background: Environmental exposure chambers have been used to expose subjects to aeroallergens to investigate the efficacy of prophylactic treatment with symptomatic agents in Japan. We first examined the therapeutic effect...
8.
Okamoto Y, Okubo K, Yonekura S, Hashiguchi K, Goto M, Otsuka T, et al.
Int Arch Allergy Immunol
. 2015 Apr;
166(3):177-88.
PMID: 25895909
Background: Japanese cedar (JC) pollinosis is the most common seasonal allergic rhinitis in Japan. Standardized JC pollen extract is available for subcutaneous immunotherapy, but this treatment is limited by potentially...
9.
Gotoh M, Okubo K, Hashiguchi K, Wakabayashi K, Kanzaki S, Tanaka N, et al.
Allergy Asthma Proc
. 2013 Feb;
33(6):459-66.
PMID: 23394502
Pranlukast (PLK) is a cysteinyl leukotriene receptor 1 antagonist approved for the treatment of bronchial asthma and allergic rhinitis in Japan. We previously reported that PLK dry syrup (DS) improved...
10.
Wakabayashi K, Hashiguchi K, Kanzaki S, Fujioka M, Tanaka N, Kawashima K, et al.
Allergy Asthma Proc
. 2012 Feb;
33(1):102-9.
PMID: 22370535
Pranlukast (PLK) is a leukotriene receptor antagonist (LTRA) that has been approved for treatment of asthma in patients of all ages and allergic rhinitis (AR) in adults but not for...