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Kay Childs

Explore the profile of Kay Childs including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 386
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Recent Articles
1.
Riccio S, Childs K, Jackson B, Graham S, Seago J
Viruses . 2023 Dec; 15(12). PMID: 38140685
Porcine reproductive and respiratory syndrome viruses (PRRSV-1 and -2) are the causative agents of one of the most important infectious diseases affecting the global pig industry. Previous studies, largely focused...
2.
Childs K, Harvey Y, Waters R, Woma T, Wilsden G, Sun H, et al.
Vaccine . 2023 Sep; 41(44):6572-6578. PMID: 37679279
Foot-and-mouth disease (FMD) is a highly contagious viral disease of livestock which is prevalent across Africa, the Middle East, Asia, and South America where it has a severe economic impact...
3.
Childs K, Jackson B, Harvey Y, Seago J
Viruses . 2022 Jun; 14(6). PMID: 35746633
Foot-and-mouth disease is an economically devastating disease of livestock caused by foot-and-mouth disease virus (FMDV). Vaccination is the most effective control measure in place to limit the spread of the...
4.
Harvey Y, Jackson B, Carr B, Childs K, Moffat K, Freimanis G, et al.
Viruses . 2022 Mar; 14(3). PMID: 35337028
Foot-and-mouth disease (FMD) is endemic in large parts of sub-Saharan Africa, Asia and South America, where outbreaks in cloven-hooved livestock threaten food security and have severe economic impacts. Vaccination in...
5.
Childs K, Juleff N, Moffat K, Seago J
Viruses . 2021 Dec; 13(12). PMID: 34960702
Foot-and-mouth disease, caused by foot-and-mouth disease virus (FMDV), is an economically devastating disease affecting several important livestock species. FMDV is antigenically diverse and exists as seven serotypes comprised of many...
6.
Iaconis G, Jackson B, Childs K, Boyce M, Goodbourn S, Blake N, et al.
Viruses . 2021 Apr; 13(4). PMID: 33807175
Type I interferons (IFNs) are produced by most cells in response to virus infection and stimulate a program of anti-viral gene expression in neighboring cells to suppress virus replication. Type...
7.
Mohamoud H, Ahmed S, Jelani M, Alrayes N, Childs K, Vadgama N, et al.
Sci Rep . 2018 Feb; 8(1):2053. PMID: 29391579
Childhood onset clinical syndromes involving intellectual disability and dysmorphic features, such as polydactyly, suggest common developmental pathways link seemingly unrelated phenotypes. We identified a consanguineous family of Saudi origin with...
8.
Childs K, Randall R, Goodbourn S
J Virol . 2012 Feb; 86(7):3411-21. PMID: 22301134
RIG-I and mda-5 are activated by viral RNA and stimulate type I interferon production. Laboratory of genetics and physiology 2 (LGP2) shares homology with RIG-I and mda-5 but lacks the...
9.
Zhang F, Moon A, Childs K, Goodbourn S, Dixon L
J Virol . 2010 Aug; 84(20):10681-9. PMID: 20702639
The African swine fever virus (ASFV) DP71L protein is present in all isolates as either a short form of 70 to 72 amino acids or a long form of about...
10.
Childs K, Stock N, Ross C, Andrejeva J, Hilton L, Skinner M, et al.
Virology . 2006 Oct; 359(1):190-200. PMID: 17049367
The induction of IFN-beta by the paramyxovirus PIV5 (formerly known as SV5) is limited by the action of the viral V protein that targets the cellular RNA helicase mda-5. Here...