Katsuhiro Mori
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Explore the profile of Katsuhiro Mori including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
470
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Recent Articles
1.
Yamasaki K, Kaneko E, Mori K
Monoclon Antib Immunodiagn Immunother
. 2022 Jun;
41(3):125-132.
PMID: 35736627
Therapeutic agents targeting B cells, such as rituximab, have been proven to be effective in several diseases. However, since this therapy targets the whole B cell population, there are still...
2.
Iida S, Kuni-Kamochi R, Mori K, Misaka H, Inoue M, Okazaki A, et al.
BMC Cancer
. 2009 Feb;
9:58.
PMID: 19226457
Background: Antibody-dependent cellular cytotoxicity (ADCC) has recently been identified as one of the critical mechanisms underlying the clinical efficacy of therapeutic antibodies, especially anticancer antibodies. Therapeutic antibodies fully lacking the...
3.
Shibata-Koyama M, Iida S, Misaka H, Mori K, Yano K, Shitara K, et al.
Exp Hematol
. 2009 Feb;
37(3):309-21.
PMID: 19218011
Objective: Antibody-dependent cellular cytotoxicity mediated by natural killer cells via leukocyte receptor IIIa (FcgammaRIIIa) is greatly enhanced by the absence of the core fucose of Fc oligosaccharides, and is closely...
4.
Mori K, Iida S, Yamane-Ohnuki N, Kanda Y, Kuni-Kamochi R, Nakano R, et al.
Cytotechnology
. 2008 Nov;
55(2-3):109-14.
PMID: 19003000
Therapeutic antibody IgG1 has two N-linked oligosaccharide chains bound to the Fc region. The oligosaccharides are of the complex biantennary type, composed of a trimannosyl core structure with the presence...
5.
Shibata-Koyama M, Iida S, Okazaki A, Mori K, Kitajima-Miyama K, Saitou S, et al.
Glycobiology
. 2008 Oct;
19(2):126-34.
PMID: 18952826
Human leukocyte receptor IIIa (Fc gamma RIIIa) plays an important role in mediating therapeutic antibodies' antibody-dependent cellular cytotoxicity (ADCC), which is closely related to the clinical efficacy of anticancer processes...
6.
Imai-Nishiya H, Mori K, Inoue M, Wakitani M, Iida S, Shitara K, et al.
BMC Biotechnol
. 2007 Dec;
7:84.
PMID: 18047682
Background: Antibody-dependent cellular cytotoxicity (ADCC) is greatly enhanced by the absence of the core fucose of oligosaccharides attached to the Fc, and is closely related to the clinical efficacy of...
7.
Kanda Y, Imai-Nishiya H, Kuni-Kamochi R, Mori K, Inoue M, Kitajima-Miyama K, et al.
J Biotechnol
. 2007 Jun;
130(3):300-10.
PMID: 17559959
Currently, removal of core fucose from the Fc oligosaccharides of therapeutic antibodies is widely recognized as being of great importance for the effector function of antibody-dependent cellular cytotoxicity, and alpha-1,6-fucosyltransferase...
8.
Yamano K, Mori K, Nakano R, Kusunoki M, Inoue M, Satoh M
Transgenic Res
. 2007 Mar;
16(4):429-35.
PMID: 17387626
To investigate the functional expression of adenosine A3 receptor (A3AR) in mammalian living tissues, we generated an apoaequorin-transgenic mouse that expresses jellyfish apoaequorin throughout its body. The expression of apoaequorin...
9.
Kanda Y, Yamada T, Mori K, Okazaki A, Inoue M, Kitajima-Miyama K, et al.
Glycobiology
. 2006 Oct;
17(1):104-18.
PMID: 17012310
The structure of asparagine-linked oligosaccharides attached to the antibody constant region (Fc) of human immunoglobulin G1 (IgG1) has been shown to affect the pharmacokinetics and antibody effector functions of antibody-dependent...
10.
Mori K, Kuni-Kamochi R, Yamane-Ohnuki N, Wakitani M, Yamano K, Imai H, et al.
Biotechnol Bioeng
. 2004 Oct;
88(7):901-8.
PMID: 15515168
We explored the possibility of converting established antibody-producing cells to cells producing high antibody-dependent cellular cytotoxicity (ADCC) antibodies. The conversion was made by constitutive expression of small interfering RNA (siRNA)...