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Katrin Karbstein

Explore the profile of Katrin Karbstein including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 1835
Followers 0
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Recent Articles
1.
Tutak K, Karbstein K
Nat Cell Biol . 2025 Feb; 27(3):377-378. PMID: 39934333
No abstract available.
2.
Yang Y, Karbstein K
bioRxiv . 2024 Aug; PMID: 39185221
Rps26-deficient ribosomes are a physiologically relevant ribosome population which arises during osmotic stress to support the translation of mRNAs involved in the response to high salt in yeast. They are...
3.
Parker M, Brunk E, Getzler A, Karbstein K
PLoS Biol . 2024 Jul; 22(4):e3001767. PMID: 39038273
The 18S rRNA sequence is highly conserved, particularly at its 3'-end, which is formed by the endonuclease Nob1. How Nob1 identifies its target sequence is not known, and in vitro...
4.
Yang Y, Karbstein K
Annu Rev Cell Dev Biol . 2024 May; 40(1):241-264. PMID: 38724022
Ribosomes synthesize protein in all cells. Maintaining both the correct number and composition of ribosomes is critical for protein homeostasis. To address this challenge, cells have evolved intricate quality control...
5.
Blomqvist E, Huang H, Karbstein K
PLoS Genet . 2023 Nov; 19(11):e1010862. PMID: 37910572
Ribosomes are complex macromolecules assembled from 4 rRNAs and 79 ribosomal proteins (RPs). Their assembly is organized in a highly hierarchical manner, which is thought to avoid dead-end pathways, thereby...
6.
Blomqvist E, Huang H, Karbstein K
bioRxiv . 2023 Jul; PMID: 37503067
Ribosomes are complex macromolecules assembled from 4 rRNAs and 79 ribosomal proteins (RPs). Their assembly is organized in a highly hierarchical manner, which is thought to avoid dead-end pathways, thereby...
7.
Yang Y, Jung Y, Abegg D, Adibekian A, Carroll K, Karbstein K
Mol Cell . 2023 Apr; 83(9):1527-1537.e5. PMID: 37086725
Because of the central role ribosomes play for protein translation and ribosome-mediated mRNA and protein quality control (RQC), the ribosome pool is surveyed and dysfunctional ribosomes degraded both during assembly,...
8.
Parker M, Karbstein K
J Cell Biol . 2023 Feb; 222(4). PMID: 36790396
The coordinated integration of ribosomal RNA and protein into two functional ribosomal subunits is safeguarded by quality control checkpoints that ensure ribosomes are correctly assembled and functional before they engage...
9.
Karbstein K
Methods Enzymol . 2022 Aug; 673:19-38. PMID: 35965007
DEAD-box proteins are a subfamily of ATPases with similarity to RecA-type helicases that are involved in all aspects of RNA Biology. Despite their potential to regulate these processes via their...
10.
Barna M, Karbstein K, Tollervey D, Ruggero D, Brar G, Greer E, et al.
Mol Cell . 2022 Jun; 82(12):2179-2184. PMID: 35714581
The concept of specialized ribosomes has garnered equal amounts of interest and skepticism since it was first introduced. We ask researchers in the field to provide their perspective on the...