Katrin Deiser
Overview
Explore the profile of Katrin Deiser including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
338
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Recent Articles
1.
Schmitt S, Tahk S, Lohner A, Hanel G, Maiser A, Hauke M, et al.
Front Immunol
. 2020 Dec;
11:602802.
PMID: 33281829
Conventional dendritic cell (DC) vaccine strategies, in which DCs are loaded with antigens , suffer biological issues such as impaired DC migration capacity and laborious GMP production procedures. In a...
2.
Lichtenegger F, Schnorfeil F, Rothe M, Deiser K, Altmann T, Bucklein V, et al.
Clin Transl Immunology
. 2020 Mar;
9(3):e1117.
PMID: 32153780
Objectives: Innovative post-remission therapies are needed to eliminate residual AML cells. DC vaccination is a promising strategy to induce anti-leukaemic immune responses. Methods: We conducted a first-in-human phase I study...
3.
Bank U, Deiser K, Plaza-Sirvent C, Osbelt L, Witte A, Knop L, et al.
Nat Commun
. 2020 Feb;
11(1):1056.
PMID: 32103006
NKp46 innate lymphoid cells (ILC) modulate tissue homeostasis and anti-microbial immune responses. ILC development and function are regulated by cytokines such as Interleukin (IL)-7 and IL-15. However, the ILC-intrinsic pathways...
4.
Knop L, Deiser K, Bank U, Witte A, Mohr J, Philipsen L, et al.
Eur J Immunol
. 2020 Feb;
50(6):846-857.
PMID: 32043573
The survival of peripheral T cells is dependent on their access to peripheral LNs (pLNs) and stimulation by IL-7. In pLNs fibroblastic reticular cells (FRCs) and lymphatic endothelial cells (LECs)...
5.
Knop L, Frommer C, Stoycheva D, Deiser K, Kalinke U, Blankenstein T, et al.
Front Immunol
. 2019 Feb;
10:140.
PMID: 30792713
In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to lymphopenia. Several lymphopenia-insensitive T cell clones were described and...
6.
Herrmann M, Krupka C, Deiser K, Brauchle B, Marcinek A, Wagner A, et al.
Blood
. 2018 Oct;
132(23):2484-2494.
PMID: 30275109
The CD33-targeting bispecific T-cell engager (BiTE) AMG 330 proved to be highly efficient in mediating cytolysis of acute myeloid leukemia (AML) cells in vitro and in mouse models. Yet, T-cell...
7.
Lichtenegger F, Rothe M, Schnorfeil F, Deiser K, Krupka C, Augsberger C, et al.
Front Immunol
. 2018 Mar;
9:385.
PMID: 29535740
Immune checkpoint inhibition has been shown to successfully reactivate endogenous T cell responses directed against tumor-associated antigens, resulting in significantly prolonged overall survival in patients with various tumor entities. For...
8.
Deiser K, Stoycheva D, Bank U, Blankenstein T, Schuler T
PLoS One
. 2016 Jul;
11(7):e0159690.
PMID: 27447484
The adoptive transfer of antigen-specific CD8+ T cells is a promising approach for the treatment of chronic viral and malignant diseases. In order to improve adoptive T cell therapy (ATT)...
9.
Bank U, Deiser K, Finke D, Hammerling G, Arnold B, Schuler T
J Immunol
. 2016 Mar;
196(9):3532-6.
PMID: 26983785
In adult mice, lymphopenia-induced proliferation (LIP) leads to T cell activation, memory differentiation, tissue destruction, and a loss of TCR diversity. Neonatal mice are lymphopenic within the first week of...
10.
Stoycheva D, Deiser K, Starck L, Nishanth G, Schluter D, Uckert W, et al.
J Immunol
. 2014 Dec;
194(2):553-9.
PMID: 25480562
In response to primary Ag contact, naive mouse CD8(+) T cells undergo clonal expansion and differentiate into effector T cells. After pathogen clearance, most effector T cells die, and only...