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Kathryn M Stevens

Explore the profile of Kathryn M Stevens including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 84
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Recent Articles
1.
Hocher A, Laursen S, Radford P, Tyson J, Lambert C, Stevens K, et al.
Nat Microbiol . 2024 May; 9(11):3075. PMID: 38778207
No abstract available.
2.
Hocher A, Laursen S, Radford P, Tyson J, Lambert C, Stevens K, et al.
Nat Microbiol . 2023 Oct; 8(11):2006-2019. PMID: 37814071
Histone proteins bind DNA and organize the genomes of eukaryotes and most archaea, whereas bacteria rely on different nucleoid-associated proteins. Homology searches have detected putative histone-fold domains in a few...
3.
Saleh A, Noguchi Y, Aramayo R, Ivanova M, Stevens K, Montoya A, et al.
Nat Commun . 2022 May; 13(1):2915. PMID: 35614055
The controlled assembly of replication forks is critical for genome stability. The Dbf4-dependent Cdc7 kinase (DDK) initiates replisome assembly by phosphorylating the MCM2-7 replicative helicase at the N-terminal tails of...
4.
Stevens K, Warnecke T
Semin Cell Dev Biol . 2022 Feb; 135:50-58. PMID: 35221208
Exchanging core histones in the nucleosome for paralogous variants can have important functional ramifications. Many of these variants, and their physiological roles, have been characterized in exquisite detail in model...
5.
Stevens K, Hocher A, Warnecke T
Genome Biol Evol . 2021 Dec; 14(1). PMID: 34894218
Histones are ubiquitous in eukaryotes where they assemble into nucleosomes, binding and wrapping DNA to form chromatin. One process to modify chromatin and regulate DNA accessibility is the replacement of...
6.
Stevens K, Swadling J, Hocher A, Bang C, Gribaldo S, Schmitz R, et al.
Proc Natl Acad Sci U S A . 2020 Dec; 117(52):33384-33395. PMID: 33288720
Nucleosomes in eukaryotes act as platforms for the dynamic integration of epigenetic information. Posttranslational modifications are reversibly added or removed and core histones exchanged for paralogous variants, in concert with...
7.
Rojec M, Hocher A, Stevens K, Merkenschlager M, Warnecke T
Elife . 2019 Nov; 8. PMID: 31692448
Nucleosomes restrict DNA accessibility throughout eukaryotic genomes, with repercussions for replication, transcription, and other DNA-templated processes. How this globally restrictive organization emerged during evolution remains poorly understood. Here, to better...