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Kathryn M Kauffman

Explore the profile of Kathryn M Kauffman including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 618
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Recent Articles
1.
Matrishin C, Haase E, Dewhirst F, Welch J, Miranda-Sanchez F, Chen T, et al.
Microbiome . 2024 Aug; 12(1):144. PMID: 39098895
No abstract available.
2.
Baker J, Welch J, Kauffman K, McLean J, He X
Nat Rev Microbiol . 2023 Sep; 22(2):89-104. PMID: 37700024
The human oral microbiota is highly diverse and has a complex ecology, comprising bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and highly structured biogeography that shapes metabolic exchange...
3.
Matrishin C, Haase E, Dewhirst F, Welch J, Miranda-Sanchez F, Chen T, et al.
Microbiome . 2023 Jul; 11(1):161. PMID: 37491415
Background: Porphyromonas gingivalis (hereafter "Pg") is an oral pathogen that has been hypothesized to act as a keystone driver of inflammation and periodontal disease. Although Pg is most readily recovered...
4.
Piel D, Bruto M, Labreuche Y, Blanquart F, Goudenege D, Barcia-Cruz R, et al.
Nat Microbiol . 2022 Jun; 7(7):1075-1086. PMID: 35760840
Coevolution between bacteriophages (phages) and their bacterial hosts occurs through changes in resistance and counter-resistance mechanisms. To assess phage-host evolution in wild populations, we isolated 195 Vibrio crassostreae strains and...
5.
Kauffman K, Chang W, Brown J, Hussain F, Yang J, Polz M, et al.
Nat Commun . 2022 Jan; 13(1):372. PMID: 35042853
Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages) and bacteria are interacting is a major challenge in the context of natural levels of microbial diversity. Thus,...
6.
Yang J, Fang W, Miranda-Sanchez F, Brown J, Kauffman K, Acevero C, et al.
Cell Syst . 2021 Jun; 12(8):771-779.e5. PMID: 34143976
Viruses are traditionally thought to be under selective pressure to maintain compact genomes and thus depend on host cell translational machinery for reproduction. However, some viruses encode abundant tRNA and...
7.
Kirchberger P, Orata F, Nasreen T, Kauffman K, Tarr C, Case R, et al.
Environ Microbiol . 2020 Jan; 22(10):4244-4256. PMID: 31970854
Populations of the bacterium Vibrio cholerae consist of dozens of distinct lineages, with primarily (but not exclusively) members of the pandemic generating lineage capable of causing the diarrhoeal disease cholera....
8.
Zhao S, Lieberman T, Poyet M, Kauffman K, Gibbons S, Groussin M, et al.
Cell Host Microbe . 2019 Apr; 25(5):656-667.e8. PMID: 31028005
Natural selection shapes bacterial evolution in all environments. However, the extent to which commensal bacteria diversify and adapt within the human gut remains unclear. Here, we combine culture-based population genomics...
9.
Kauffman K, Polz M
MethodsX . 2019 Jan; 5:159-172. PMID: 30622914
A universal tool in the culture-based study of bacterial viruses (bacteriophages, or phages) is the agar overlay, which is used in the isolation of new viruses, and in their quantification...
10.
Kauffman K, Brown J, Sharma R, VanInsberghe D, Elsherbini J, Polz M, et al.
Sci Data . 2018 Jul; 5:180114. PMID: 29969110
Viruses are highly discriminating in their interactions with host cells and are thought to play a major role in maintaining diversity of environmental microbes. However, large-scale ecological and genomic studies...