Kathryn E DeSear
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Explore the profile of Kathryn E DeSear including associated specialties, affiliations and a list of published articles.
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7
Citations
20
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Recent Articles
1.
Shields R, Abbo L, Ackley R, Aitken S, Albrecht B, Babiker A, et al.
Lancet Infect Dis
. 2024 Dec;
PMID: 39701120
Background: Ceftolozane-tazobactam and ceftazidime-avibactam are preferred treatment options for multidrug-resistant Pseudomonas aeruginosa infections; however, real-world comparative effectiveness studies are scarce. Pharmacokinetic and pharmacodynamic differences between the agents might affect clinical...
2.
Branton A, Vu C, Venugopalan V, Santevecchi B, Cherabuddi K, Ramphal R, et al.
JAC Antimicrob Resist
. 2023 Mar;
5(2):dlad021.
PMID: 36936190
Objectives: To re-examine the use of non-carbapenems (NCBPs), specifically piperacillin/tazobactam and cefepime, for ESBL-producing Enterobacterales (ESBL-E) urinary tract infections (UTIs). Patients: Retrospective cohort study of adults hospitalized between January 2016...
3.
Zhai Y, Lee S, Teng L, Ma Z, Hilliard N, May R, et al.
JAC Antimicrob Resist
. 2021 Jul;
3(1):dlab032.
PMID: 34223104
Background: NDM-producing Enterobacteriaceae are a major clinical concern worldwide. We characterized NDM-positive pathogens isolated from patients and assessed the dissemination patterns of the genes in a hospital setting. Methods: Eleven...
4.
Zhai Y, DeSear K, Cherabuddi K, Morris Jr J, Jeong K
Microbiol Resour Announc
. 2021 Mar;
10(11).
PMID: 33737360
complex (Bcc) bacteria are opportunistic pathogens with high transmissibility and mortality. Here, we report the draft genome sequence of a Bcc strain isolated from a deep abscess culture in an...
5.
DeSear K, Thompson-Leduc P, Van Schooneveld T, Kirson N, Chritton J, Ie S, et al.
Curr Med Res Opin
. 2021 Feb;
37(5):727-733.
PMID: 33617362
Objective: Antibiotic overuse leading to antimicrobial resistance is a global public health concern. Clinical trials have demonstrated that procalcitonin-based decision-making for antibiotic therapy can safely decrease inappropriate antibiotic use in...
6.
DeSear K, Thompson-Leduc P, Kirson N, Chritton J, Ie S, Van Schooneveld T, et al.
Curr Med Res Opin
. 2020 Jul;
36(9):1529-1532.
PMID: 32643964
Objective: Procalcitonin (PCT) is a biomarker that may help providers optimize antibiotic (AB) therapy. Numerous clinical trials have demonstrated the utility of PCT-guided decision algorithms in treating lower respiratory tract...
7.
Huesgen E, DeSear K, Egelund E, Smith R, Max B, Janelle J
Pharmacotherapy
. 2016 Sep;
36(11):1145-1165.
PMID: 27636237
Selection of an appropriate antiretroviral regimen for the patient infected with human immunodeficiency virus can be challenging, as various considerations must be taken into account including viral resistance mutations, patient...