Kathleen M Frey
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Explore the profile of Kathleen M Frey including associated specialties, affiliations and a list of published articles.
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35
Citations
488
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Recent Articles
1.
Hollander K, Chan A, Frey K, Hunker O, Ippolito J, Spasov K, et al.
Protein Sci
. 2023 Oct;
32(12):e4814.
PMID: 37861472
HIV-1 reverse transcriptase (RT) remains a key target for HIV drug development. As successful management of the disease requires lifelong treatment, the emergence of resistance mutations is inevitable, making development...
2.
Lange K, Frey K, Eck T, Janson C, Gubler U, Goodey N
PLoS Negl Trop Dis
. 2023 Apr;
17(4):e0011303.
PMID: 37104530
Lymphatic filariasis is a debilitating illness with an estimated 50 million cases as of 2018. The majority of cases are caused by the parasitic worm W. bancrofti and additional cases...
3.
Frey K, Bertoletti N, Chan A, Ippolito J, Bollini M, Spasov K, et al.
Front Mol Biosci
. 2022 Mar;
9:805187.
PMID: 35237658
Reverse transcriptase (RT) from the human immunodeficiency virus continues to be an attractive drug target for antiretroviral therapy. June 2022 will commemorate the 30th anniversary of the first Human Immunodeficiency...
4.
Kalabalik-Hoganson J, Frey K, Ozdener-Poyraz A, Slugocki M
Ann Pharmacother
. 2021 Feb;
55(10):1290-1296.
PMID: 33533262
Objective: To review the efficacy and safety of clascoterone 1% cream for the treatment of acne vulgaris in patients 12 years of age and older. Data Sources: A literature search...
5.
Serris I, Serris P, Frey K, Cho H
AAPS PharmSciTech
. 2020 Sep;
21(7):256.
PMID: 32888114
3D printing has been widely used to rapidly manufacture a variety of solid dosage forms on-demand, without sacrificing precision. This study used extrusion-based 3D printing to prepare single-layered, tri-layered, and...
6.
Patel M, Narke D, Kurade M, Frey K, Rajalingam S, Siddiquee A, et al.
Purinergic Signal
. 2020 Aug;
16(3):415-426.
PMID: 32789792
Animal models of asthma have shown that limonene, a naturally occurring terpene in citrus fruits, can reduce inflammation and airway reactivity. However, the mechanism of these effects is unknown. We...
7.
Tabassum T, Azeem S, Muwonge A, Frey K
Curr HIV Res
. 2020 Jun;
18(4):283-291.
PMID: 32493197
Background: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are used in combination with antiretroviral therapy to suppress viral loads in HIV patients. The chemical design of NNRTIs has changed in recent years...
8.
Frey K
Curr Pharm Teach Learn
. 2020 Apr;
12(3):339-346.
PMID: 32273073
Background And Purpose: Courses that integrate pharmacology, medicinal chemistry, and pharmacotherapy are widely implemented in pharmacy curriculums. The integration of medicinal chemistry is often challenging given the difficulty of material...
9.
Sasaki T, Gannam Z, Kudalkar S, Frey K, Lee W, Spasov K, et al.
Bioorg Med Chem Lett
. 2019 Jul;
29(16):2182-2188.
PMID: 31281023
The development of efficacious NNRTIs for HIV/AIDS therapy is commonly met with the emergence of drug resistant strains, including the Y181C variant. Using a computationally-guided approach, we synthesized the catechol...
10.
Tetenbaum-Novatt J, Lonie J, Elkowitz D, Frey K
Curr Pharm Teach Learn
. 2018 Dec;
10(11):1529-1540.
PMID: 30514546
Background And Purpose: This project investigates the use of pharmacy student metacognitive learning in a laboratory-based science research advanced pharmacy practice experience (APPE). Educational Activity And Setting: We describe a...