Kathleen M Botham
Overview
Explore the profile of Kathleen M Botham including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
408
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Recent Articles
1.
Garonna E, Botham K, Birdsey G, Randi A, Gonzalez-Perez R, Wheeler-Jones C
PLoS One
. 2019 Oct;
14(9):e0223400.
PMID: 31568534
[This corrects the article DOI: 10.1371/journal.pone.0018823.].
2.
Latham Birt S, Purcell R, Botham K, Wheeler-Jones C
J Lipid Res
. 2016 May;
57(7):1204-18.
PMID: 27185859
Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown...
3.
Botham K, Napolitano M, Bravo E
Nutrients
. 2015 Dec;
7(12):9834-46.
PMID: 26633474
Although non-alcoholic fatty liver disease (NAFLD), characterised by the accumulation of triacylglycerol in the liver, is the most common liver disorder, the causes of its development and progression to the...
4.
Cabello-Moruno R, Sinausia L, Botham K, Montero E, Avella M, Perona J
Br J Nutr
. 2014 Sep;
112(9):1469-77.
PMID: 25245985
Postprandial TAG-rich lipoproteins (TRL) can be taken up by macrophages, leading to the formation of foam cells, probably via receptor-mediated pathways. The present study was conducted to investigate whether the...
5.
Purcell R, Latham S, Botham K, Hall W, Wheeler-Jones C
Am J Clin Nutr
. 2014 Aug;
100(4):1019-28.
PMID: 25099540
Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine...
6.
Dawson H, Hibbert A, Chantler P, Botham K
Int J Vasc Med
. 2013 Jul;
2013:516015.
PMID: 23840954
Myosin VI (Myo6) functions in endocytosis in conjunction with binding partners including adaptor protein (AP)-2, disabled 2 (Dab2), and GAIP interacting protein C terminus 1 (GIPC1). This study aimed to...
7.
Botham K, Wheeler-Jones C
Prog Lipid Res
. 2013 Jun;
52(4):446-64.
PMID: 23774609
Blood levels of triglyceride-rich lipoproteins (TRL) increase postprandially, and a delay in their clearance results in postprandial hyperlipidemia, an important risk factor in atherosclerosis development. Atherosclerosis is a multifactorial inflammatory...
8.
Napolitano M, Botham K, Bravo E
Cytokine
. 2013 May;
63(1):18-26.
PMID: 23683858
This study tested the hypothesis that postprandial triglyceride-rich lipoproteins (ppTGRL) have inflammatory effects in primary human monocyte-derived macrophages (HMDM). ppTGRL were isolated from normolipidemic human volunteers, and the production of...
9.
Napolitano M, Sennato S, Botham K, Bordi F, Bravo E
Exp Biol Med (Maywood)
. 2013 Mar;
238(1):98-110.
PMID: 23479769
The potential link between the inflammatory effects of postprandial lipemia and the induction of macrophage foam cell formation by triacylglycerol-rich lipoproteins (TGRL) was studied using postprandial triacylglycerol-rich lipoproteins (ppTGRL) derived...
10.
Cabezas M, Botham K, Mamo J, Proctor S
Int J Vasc Med
. 2012 May;
2012:419015.
PMID: 22548177
No abstract available.