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Katherine S Elliott

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Recent Articles
1.
Binks S, Elliott K, Muniz-Castrillo S, Gilbert E, Kawasaki de Araujo T, Harper A, et al.
Brain . 2024 Oct; 148(3):737-745. PMID: 39454566
Encephalitis with antibodies to leucine-rich glioma-inactivated 1 (LGI1-Ab-E) is a common form of autoimmune encephalitis, presenting with seizures and neuropsychiatric changes, predominantly in older males. More than 90% of patients...
2.
Hagele P, Staus P, Scheible R, Uhlmann A, Heeg M, Klemann C, et al.
Lancet Haematol . 2024 Feb; 11(2):e114-e126. PMID: 38302222
Background: Lymphoproliferation and autoimmune cytopenias characterise autoimmune lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed autoimmune lymphoproliferative syndrome-like diseases, although they are frequently more severe. The aim of...
3.
Brown A, Cohen C, Mielczarek O, Migliorini G, Costantino F, Allcock A, et al.
Cell Genom . 2023 Jun; 3(6):100306. PMID: 37388915
Ankylosing spondylitis (AS) is a common, highly heritable inflammatory arthritis characterized by enthesitis of the spine and sacroiliac joints. Genome-wide association studies (GWASs) have revealed more than 100 genetic associations...
4.
Kousathanas A, Pairo-Castineira E, Rawlik K, Stuckey A, Odhams C, Walker S, et al.
Nature . 2022 Mar; 607(7917):97-103. PMID: 35255492
Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of...
5.
Elliott K, Haber M, Daggag H, Busby G, Sarwar R, Kennet D, et al.
Mol Biol Evol . 2022 Feb; 39(3). PMID: 35192718
The indigenous population of the United Arab Emirates (UAE) has a unique demographic and cultural history. Its tradition of endogamy and consanguinity is expected to produce genetic homogeneity and partitioning...
6.
Peris Sempere V, Muniz-Castrillo S, Ambati A, Binks S, Pinto A, Rogemond V, et al.
Neurol Neuroimmunol Neuroinflamm . 2022 Feb; 9(2). PMID: 35115410
Background And Objectives: To study human leukocyte antigen (HLA) allele associations in anti-leucine-rich glioma-inactivated 1 (LGI1) encephalitis. Methods: A multiethnic cohort of 269 patients with anti-LGI1 encephalitis and 1,359 controls...
7.
Symonds J, Elliott K, Shetty J, Armstrong M, Brunklaus A, Cutcutache I, et al.
Brain . 2021 Oct; 144(9):2879-2891. PMID: 34687210
Epilepsies of early childhood are frequently resistant to therapy and often associated with cognitive and behavioural comorbidity. Aetiology focused precision medicine, notably gene-based therapies, may prevent seizures and comorbidities. Epidemiological...
8.
Hadjadj J, Castro C, Tusseau M, Stolzenberg M, Mazerolles F, Aladjidi N, et al.
Nat Commun . 2020 Oct; 11(1):5341. PMID: 33087723
Autoimmunity can occur when a checkpoint of self-tolerance fails. The study of familial autoimmune diseases can reveal pathophysiological mechanisms involved in more common autoimmune diseases. Here, by whole-exome/genome sequencing we...
9.
Blok L, Hiatt S, Bowling K, Prokop J, Engel K, Cochran J, et al.
Hum Genet . 2018 May; 137(5):375-388. PMID: 29740699
Many genetic causes of developmental delay and/or intellectual disability (DD/ID) are extremely rare, and robust discovery of these requires both large-scale DNA sequencing and data sharing. Here we describe a...
10.
Winsvold B, Nelson C, Malik R, Gormley P, Anttila V, Vander Heiden J, et al.
Neurol Genet . 2016 Apr; 1(1):e10. PMID: 27066539
Objective: To apply genetic analysis of genome-wide association data to study the extent and nature of a shared biological basis between migraine and coronary artery disease (CAD). Methods: Four separate...