Katherine M Rentschler
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Explore the profile of Katherine M Rentschler including associated specialties, affiliations and a list of published articles.
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9
Citations
55
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Recent Articles
1.
Rentschler K, Kodavanti U
Crit Rev Toxicol
. 2024 Dec;
54(10):953-980.
PMID: 39655487
Air pollution is a significant environmental health risk for urban areas and developing countries. Air pollution may contribute to the incidence of cardiopulmonary and metabolic diseases. Evidence also points to...
2.
Alewel D, Jackson T, Rentschler K, Schladweiler M, Astriab-Fisher A, Gavett S, et al.
Front Toxicol
. 2023 Dec;
5:1280230.
PMID: 38090360
Acrolein is a significant component of anthropogenic and wildfire emissions, as well as cigarette smoke. Although acrolein primarily deposits in the upper respiratory tract upon inhalation, patterns of site-specific injury...
3.
Alewel D, Rentschler K, Jackson T, Schladweiler M, Astriab-Fisher A, Evansky P, et al.
Sci Rep
. 2023 Dec;
13(1):21179.
PMID: 38040807
Acrolein, a respiratory irritant, induces systemic neuroendocrine stress. However, peripheral metabolic effects have not been examined. Male and female WKY rats were exposed to air (0 ppm) or acrolein (3.16 ...
4.
Rentschler K, Milosavljevic S, Baratta A, Wright C, Piroli M, Tentor Z, et al.
J Sleep Res
. 2023 Sep;
33(3):e14038.
PMID: 37678806
Patients with neurocognitive disorders often battle sleep disturbances. Kynurenic acid is a tryptophan metabolite of the kynurenine pathway implicated in the pathology of these illnesses. Modest increases in kynurenic acid,...
5.
Smith A, Anand H, Milosavljevic S, Rentschler K, Pocivavsek A, Valafar H
Proc (Int Conf Comput Sci Comput Intell)
. 2022 Oct;
2021:349-354.
PMID: 36313065
Sleep studies are imperative to recapitulate phenotypes associated with sleep loss and uncover mechanisms contributing to psychopathology. Most often, investigators manually classify the polysomnography into vigilance states, which is time-consuming,...
6.
Wright C, Rentschler K, Wagner N, Lewis A, Beggiato S, Pocivavsek A
Front Psychiatry
. 2021 Oct;
12:734984.
PMID: 34603109
Hypofunction of glutamatergic signaling is causally linked to neurodevelopmental disorders, including psychotic disorders like schizophrenia and bipolar disorder. Kynurenic acid (KYNA) has been found to be elevated in postmortem brain...
7.
Rentschler K, Baratta A, Ditty A, Wagner N, Wright C, Milosavljevic S, et al.
Schizophr Bull
. 2021 Apr;
47(5):1320-1330.
PMID: 33823027
Dysregulation of the kynurenine pathway (KP) of tryptophan catabolism has been implicated in psychotic disorders, including schizophrenia and bipolar disorder. Kynurenic acid (KYNA) is a KP metabolite synthesized by kynurenine...
8.
Hwang J, Estick C, Ikonne U, Butler D, Pait M, Elliott L, et al.
Int J Mol Sci
. 2019 Sep;
20(18).
PMID: 31505809
Many neurodegenerative disorders have lysosomal impediments, and the list of proposed treatments targeting lysosomes is growing. We investigated the role of lysosomes in Alzheimer's disease (AD) and other age-related disorders,...
9.
Romine H, Rentschler K, Smith K, Edwards A, Colvin C, Farizatto K, et al.
Eur Sci J
. 2018 May;
13:38-59.
PMID: 29805718
Cysteine protease inhibitors have long been part of drug discovery programs for Alzheimer's disease (AD), traumatic brain injury (TBI), and other disorders. Select inhibitors reduce accumulating proteins and AD pathology...