Katherine Huppler Hullsiek
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Explore the profile of Katherine Huppler Hullsiek including associated specialties, affiliations and a list of published articles.
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54
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1907
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Recent Articles
1.
Skipper C, Hullsiek K, Stadelman A, Williams D, Ssebambulidde K, Okafor E, et al.
J Fungi (Basel)
. 2023 Jan;
9(1).
PMID: 36675867
Cryptococcus is the leading cause of AIDS-related meningitis in sub-Saharan Africa. The clinical implications of a sterile cerebrospinal fluid (CSF) culture among individuals diagnosed with cryptococcal meningitis using CSF cryptococcal...
2.
Mitja O, Reis G, Boulware D, Spivak A, Sarwar A, Johnston C, et al.
Clin Transl Sci
. 2023 Jan;
16(3):524-535.
PMID: 36601684
Hydroxychloroquine (HCQ) was initially promoted as an oral therapy for early treatment of coronavirus disease 2019 (COVID-19). Conventional meta-analyses cannot fully address the heterogeneity of different designs and outcomes of...
3.
Skipper C, Hullsiek K, Cresswell F, Tadeo K, Okirwoth M, Blackstad M, et al.
Int J Infect Dis
. 2022 Jul;
122:785-792.
PMID: 35843498
Objectives: CMV viremia is associated with increased mortality in persons with HIV. We previously demonstrated that CMV viremia was a risk factor for 10-week mortality in antiretroviral therapy (ART)-naïve persons...
4.
Lofgren S, Nicol M, Kandole T, Castillo-Mancilla J, Anderson P, Mpoza E, et al.
AIDS Res Hum Retroviruses
. 2021 Mar;
37(7):529-533.
PMID: 33677986
Early antiretroviral therapy (ART) initiation after cryptococcal meningitis increases mortality, and those unmasking cryptococcosis after <2 weeks of ART have higher mortality. However, it is unknown if those presenting as...
5.
Pullen M, Pastick K, Williams D, Nascene A, Bangdiwala A, Okafor E, et al.
Open Forum Infect Dis
. 2021 Feb;
8(2):ofaa602.
PMID: 33553471
As the severe acute respiratory syndrome coronavirus 2 pandemic evolved, it was apparent that well designed and rapidly conducted randomized clinical trials were urgently needed. However, traditional clinical trial design...
6.
Marais S, Cresswell F, Hamers R, Te Brake L, Ganiem A, Imran D, et al.
Wellcome Open Res
. 2020 Oct;
4:190.
PMID: 33083560
Tuberculous meningitis (TBM), the most severe form of tuberculosis (TB), results in death or neurological disability in >50%, despite World Health Organisation recommended therapy. Current TBM regimen dosages are based...
7.
Eneh P, Hullsiek K, Kiiza D, Rhein J, Meya D, Boulware D, et al.
BMC Infect Dis
. 2020 Aug;
20(1):572.
PMID: 32758158
Background: Management of co-infections including cryptococcal meningitis, tuberculosis and other opportunistic infections in persons living with HIV can lead to complex polypharmacotherapy and increased susceptibility to drug-drug interactions (DDIs). Here...
8.
Lofgren S, Nicol M, Bangdiwala A, Pastick K, Okafor E, Skipper C, et al.
medRxiv
. 2020 Aug;
PMID: 32743591
Introduction: Use of hydroxychloroquine in hospitalized patients with COVID-19, especially in combination with azithromycin, has raised safety concerns. Here, we report safety data from three outpatient randomized clinical trials. Methods:...
9.
Pullen M, Hullsiek K, Rhein J, Musubire A, Tugume L, Nuwagira E, et al.
Clin Infect Dis
. 2020 Jan;
71(7):e45-e49.
PMID: 31912875
Background: In cryptococcal meningitis phase 2 clinical trials, early fungicidal activity (EFA) of Cryptococcus clearance from cerebrospinal fluid (CSF) is used as a surrogate endpoint for all-cause mortality. The Food...
10.
Peterson T, Hullsiek K, Wyman Engen N, Kumarasamy N, Lebech A, Liappis A, et al.
Open Forum Infect Dis
. 2018 Jun;
5(6):ofy117.
PMID: 29942822
We estimated small arterial elasticity and used linear regression to evaluate its association with inflammatory biomarkers among antiretroviral therapy-naïve, HIV-positive patients with high CD4+ counts. After adjustment, high-sensitivity C-reactive protein...