Katherine A Grosset
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Explore the profile of Katherine A Grosset including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
791
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Recent Articles
1.
Gandhi S, Nodehi A, Lawton M, Grosset K, Marshall V, Ben-Shlomo Y, et al.
Mov Disord Clin Pract
. 2024 Jun;
11(9):1113-1124.
PMID: 38898616
Background: Dopaminergic responsiveness is a defining feature of Parkinson's disease (PD). However, there is limited information on how this evolves over time. Objectives: To examine serial dopaminergic responses, if there...
2.
Tan M, Lawton M, Pollard M, Brown E, Real R, Carrasco A, et al.
NPJ Parkinsons Dis
. 2024 Jun;
10(1):113.
PMID: 38849413
There are 90 independent genome-wide significant genetic risk variants for Parkinson's disease (PD) but currently only five nominated loci for PD progression. The biology of PD progression is likely to...
3.
Gandhi S, Zerenner T, Nodehi A, Lawton M, Marshall V, Al-Hajraf F, et al.
Mov Disord Clin Pract
. 2024 Apr;
11(6):686-697.
PMID: 38587023
Background: Motor complications are well recognized in Parkinson's disease (PD), but their reported prevalence varies and functional impact has not been well studied. Objectives: To quantify the presence, severity, impact...
4.
Heng N, Malek N, Lawton M, Nodehi A, Pitz V, Grosset K, et al.
Mov Disord Clin Pract
. 2023 Apr;
10(4):539-546.
PMID: 37070042
Background: Neuropathological studies, based on small samples, suggest that symptoms of Parkinson's disease (PD) emerge when dopamine/nigrostriatal loss is around 50-80%. Functional neuroimaging can be applied in larger numbers during...
5.
Kanavou S, Pitz V, Lawton M, Malek N, Grosset K, Morris H, et al.
Brain Behav
. 2021 Jun;
11(8):e2258.
PMID: 34190430
Objectives: Hyposmia is a common feature of Parkinson's disease (PD), yet there is no standard method to define it. A comparison of four published methods was performed to explore and...
6.
Tan M, Lawton M, Jabbari E, Reynolds R, Iwaki H, Blauwendraat C, et al.
Mov Disord
. 2020 Oct;
36(2):424-433.
PMID: 33111402
Background: There are currently no treatments that stop or slow the progression of Parkinson's disease (PD). Case-control genome-wide association studies have identified variants associated with disease risk, but not progression....
7.
Pitz V, Malek N, Tobias E, Grosset K, Gentleman S, Grosset D
Mov Disord Clin Pract
. 2020 Feb;
7(2):218-222.
PMID: 32071945
Background: A good response to levodopa is a key feature of Parkinson's disease (PD), and a poor response suggests an alternative diagnosis, but the extent of variation in the levodopa...
8.
Smith C, Cullen B, Sheridan M, Cavanagh J, Grosset K, Grosset D
Acta Neurol Scand
. 2020 Feb;
141(6):500-508.
PMID: 32002988
Background: In Parkinson's disease, mild cognitive impairment and dementia are associated with α-synuclein deposition and spread. However, coexistent Alzheimer's disease and cerebrovascular disease are common at autopsy, and may affect...
9.
Smith C, Cavanagh J, Sheridan M, Grosset K, Cullen B, Grosset D
Int J Geriatr Psychiatry
. 2019 Nov;
35(2):188-194.
PMID: 31736141
Objectives: The Montreal Cognitive Assessment (MoCA) is a common tool for screening mild cognitive impairment (MCI) and dementia. Studies in multiple clinical groups provide evidence for various factor structures mapping...
10.
Tan M, Malek N, Lawton M, Hubbard L, Pittman A, Joseph T, et al.
Brain
. 2019 Jul;
142(9):2828-2844.
PMID: 31324919
Our objective was to define the prevalence and clinical features of genetic Parkinson's disease in a large UK population-based cohort, the largest multicentre prospective clinico-genetic incident study in the world....