Katharina Borst
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Explore the profile of Katharina Borst including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
566
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Recent Articles
11.
Namineni S, OConnor T, Faure-Dupuy S, Johansen P, Riedl T, Liu K, et al.
J Hepatol
. 2020 Jan;
72(5):960-975.
PMID: 31954207
Background & Aims: Hepatic innate immune control of viral infections has largely been attributed to Kupffer cells, the liver-resident macrophages. However, hepatocytes, the parenchymal cells of the liver, also possess...
12.
Tegtmeyer P, Spanier J, Borst K, Becker J, Riedl A, Hirche C, et al.
Nat Commun
. 2019 Jun;
10(1):2830.
PMID: 31249303
Cytomegalovirus is a DNA-encoded β-herpesvirus that induces STING-dependent type 1 interferon responses in macrophages and uses myeloid cells as a vehicle for dissemination. Here we report that STING knockout mice...
13.
Borst K, Graalmann T, Kalinke U
J Hepatol
. 2019 Jun;
71(3):633-635.
PMID: 31227257
No abstract available.
14.
Borst K, Graalmann T, Kalinke U
J Hepatol
. 2019 Feb;
70(4):815-816.
PMID: 30712975
No abstract available.
15.
Tsay H, Yuan Q, Balakrishnan A, Kaiser M, Mobus S, Kozdrowska E, et al.
J Hepatol
. 2018 Dec;
70(4):722-734.
PMID: 30582979
Background & Aims: Fibrosis, a cardinal feature of a dysfunctional liver, significantly contributes to the ever-increasing mortality due to end-stage chronic liver diseases. The crosstalk between hepatocytes and hepatic stellate...
16.
Borst K, Schwabenland M, Prinz M
Neurochem Int
. 2018 Nov;
130:104331.
PMID: 30423423
In the last decade tremendous progress has been made in understanding how the immune system reacts to insults. During this progress it became obvious that those immune responses are tightly...
17.
Chhatbar C, Detje C, Grabski E, Borst K, Spanier J, Ghita L, et al.
Cell Rep
. 2018 Oct;
25(1):118-129.e4.
PMID: 30282022
In sterile neuroinflammation, a pathological role is proposed for microglia, whereas in viral encephalitis, their function is not entirely clear. Many viruses exploit the odorant system and enter the CNS...
18.
Koestner W, Spanier J, Klause T, Tegtmeyer P, Becker J, Herder V, et al.
PLoS Pathog
. 2018 Aug;
14(8):e1007235.
PMID: 30075026
During Coxsackievirus B3 (CVB3) infection hepatitis is a potentially life threatening complication, particularly in newborns. Studies with type I interferon (IFN-I) receptor (IFNAR)-deficient mice revealed a key role of the...
19.
Borst K, Frenz T, Spanier J, Tegtmeyer P, Chhatbar C, Skerra J, et al.
J Hepatol
. 2017 Dec;
68(4):682-690.
PMID: 29274730
Background & Aim: Virus-induced fulminant hepatitis is a major cause of acute liver failure. During acute viral hepatitis the impact of type I interferon (IFN-I) on myeloid cells, including liver-resident...
20.
Hirche C, Frenz T, Haas S, Doring M, Borst K, Tegtmeyer P, et al.
Cell Rep
. 2017 Jun;
19(11):2345-2356.
PMID: 28614719
Quiescent long-term hematopoietic stem cells (LT-HSCs) are efficiently activated by type I interferon (IFN-I). However, this effect remains poorly investigated in the context of IFN-I-inducing virus infections. Here we report...