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Karyl Barron

Explore the profile of Karyl Barron including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1154
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Recent Articles
1.
Goetzke C, Massoud M, Frischbutter S, Guerra G, Ferreira-Gomes M, Heinrich F, et al.
Nature . 2025 Mar; PMID: 40074901
In a subset of children and adolescents, SARS-CoV-2 infection induces a severe acute hyperinflammatory shock termed multisystem inflammatory syndrome in children (MIS-C) at four to eight weeks after infection. MIS-C...
2.
Montealegre Sanchez G, Arrigoni L, Yonts A, Rubenstein K, Bost J, Wolff M, et al.
Pediatr Res . 2024 Dec; PMID: 39695262
Background: PECOS is an ongoing study aimed to characterize long-term outcomes following pediatric SARS-CoV-2 infection. Methods: This is a cross-sectional analysis of infected and uninfected cohorts at baseline. Participants (0-21...
3.
Redmond C, Kitakule M, Son A, Sylvester M, Sacco K, Delmonte O, et al.
medRxiv . 2022 Sep; PMID: 36093351
Multisystem Inflammatory Syndrome in Children (MIS-C) is a systemic inflammatory condition that follows SARS-CoV2 infection or exposure in children. Clinical presentations are highly variable and include fever, gastrointestinal (GI) disease,...
4.
Carmona-Rivera C, Zhang Y, Dobbs K, Markowitz T, Dalgard C, Oler A, et al.
JCI Insight . 2022 Jul; 7(16). PMID: 35852866
Dysregulation in neutrophil extracellular trap (NET) formation and degradation may play a role in the pathogenesis and severity of COVID-19; however, its role in the pediatric manifestations of this disease,...
5.
Romano M, Arici Z, Piskin D, Alehashemi S, Aletaha D, Barron K, et al.
Arthritis Rheumatol . 2022 May; 74(7):1102-1121. PMID: 35621220
Background: The interleukin-1 (IL-1) mediated systemic autoinflammatory diseases, including the cryopyrin- associated periodic syndromes (CAPS), tumour necrosis factor receptor-associated periodic syndrome (TRAPS), mevalonate kinase deficiency (MKD) and deficiency of the...
6.
Burbelo P, Castagnoli R, Shimizu C, Delmonte O, Dobbs K, Discepolo V, et al.
Front Immunol . 2022 Apr; 13:841126. PMID: 35360001
The antibody profile against autoantigens previously associated with autoimmune diseases and other human proteins in patients with COVID-19 or multisystem inflammatory syndrome in children (MIS-C) remains poorly defined. Here we...
7.
Carmona-Rivera C, Zhang Y, Dobbs K, Markowitz T, Dalgard C, Oler A, et al.
medRxiv . 2022 Mar; PMID: 35262093
Summary: NET formation and degradation are dysregulated in pediatric and symptomatic adult patients with various complications of COVID-19, in association with disease severity. NET degradation impairments are multifactorial and associated...
8.
Sacco K, Castagnoli R, Vakkilainen S, Liu C, Delmonte O, Oguz C, et al.
Nat Med . 2022 Feb; 28(5):1050-1062. PMID: 35177862
Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might develop multisystem inflammatory syndrome in children (MIS-C),...
9.
Deuitch N, Yang D, Lee P, Yu X, Sampaio Moura N, Schnappauf O, et al.
J Allergy Clin Immunol . 2021 Nov; 149(5):1812-1816.e6. PMID: 34780847
Background: Deficiency of adenosine deaminase 2 (DADA2) is a recessively inherited autoinflammatory disorder caused by a loss of functional ADA2 protein. TNF inhibition (TNFi) has proven to be highly effective...
10.
Schnappauf O, Sampaio Moura N, Aksentijevich I, Stoffels M, Ombrello A, Hoffmann P, et al.
Arthritis Rheumatol . 2020 Oct; 73(3):512-519. PMID: 33021335
Objective: Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of vasculitis that can resemble polyarteritis nodosa (PAN). This study was undertaken to identify potential disease-causing sequence variants in...