Karthik Soman
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Explore the profile of Karthik Soman including associated specialties, affiliations and a list of published articles.
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15
Citations
98
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Recent Articles
1.
Jank L, Singh S, Lee J, Dhukhwa A, Siavoshi F, Joshi D, et al.
bioRxiv
. 2024 Nov;
PMID: 39554063
In multiple sclerosis (MS) the circulating metabolome is dysregulated, with indole lactate (ILA) being one of the most significantly reduced metabolites. We demonstrate that oral supplementation of ILA impacts key...
2.
Soman K, Rose P, Morris J, Akbas R, Smith B, Peetoom B, et al.
Bioinformatics
. 2024 Sep;
40(9).
PMID: 39288310
Motivation: Large language models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains such as biomedicine. Solutions such as pretraining and domain-specific fine-tuning add...
3.
Tang A, Rankin K, Cerono G, Miramontes S, Mills H, Roger J, et al.
Nat Aging
. 2024 Feb;
4(3):379-395.
PMID: 38383858
Identification of Alzheimer's disease (AD) onset risk can facilitate interventions before irreversible disease progression. We demonstrate that electronic health records from the University of California, San Francisco, followed by knowledge...
4.
Fecho K, Bizon C, Issabekova T, Moxon S, Thessen A, Abdollahi S, et al.
J Clin Transl Sci
. 2023 Oct;
7(1):e214.
PMID: 37900350
Knowledge graphs have become a common approach for knowledge representation. Yet, the application of graph methodology is elusive due to the sheer number and complexity of knowledge sources. In addition,...
5.
Soman K, Nelson C, Cerono G, Goldman S, Baranzini S, Brown E
Front Med (Lausanne)
. 2023 May;
10:1081087.
PMID: 37250641
Introduction: Early diagnosis of Parkinson's disease (PD) is important to identify treatments to slow neurodegeneration. People who develop PD often have symptoms before the disease manifests and may be coded...
6.
Morris J, Soman K, Akbas R, Zhou X, Smith B, Meng E, et al.
Bioinformatics
. 2023 Feb;
39(2).
PMID: 36759942
Motivation: Knowledge graphs (KGs) are being adopted in industry, commerce and academia. Biomedical KG presents a challenge due to the complexity, size and heterogeneity of the underlying information. Results: In...
7.
Soman K, Nelson C, Cerono G, Baranzini S
Pac Symp Biocomput
. 2022 Dec;
28:97-108.
PMID: 36540968
Meaningful representations of clinical data using embedding vectors is a pivotal step to invoke any machine learning (ML) algorithm for data inference. In this article, we propose a time-aware embedding...
8.
Unni D, Moxon S, Bada M, Brush M, Bruskiewich R, Caufield J, et al.
Clin Transl Sci
. 2022 Sep;
15(8):1848-1855.
PMID: 36125173
Within clinical, biomedical, and translational science, an increasing number of projects are adopting graphs for knowledge representation. Graph-based data models elucidate the interconnectedness among core biomedical concepts, enable data structures...
9.
Baranzini S, Borner K, Morris J, Nelson C, Soman K, Schleimer E, et al.
AI Mag
. 2022 Sep;
43(1):46-58.
PMID: 36093122
Knowledge representation and reasoning (KR&R) has been successfully implemented in many fields to enable computers to solve complex problems with AI methods. However, its application to biomedicine has been lagging...
10.
Gundavarapu A, Chakravarthy V, Soman K
Front Neurosci
. 2019 Feb;
13:67.
PMID: 30809113
Neurons in the dorsal pathway of the visual cortex are thought to be involved in motion processing. The first site of motion processing is the primary visual cortex (V1), encoding...