Karoline Kuchenbaecker
Overview
Explore the profile of Karoline Kuchenbaecker including associated specialties, affiliations and a list of published articles.
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1569
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Kalungi A, Kinyanda E, Akena D, Gelaye B, Ssembajjwe W, Mpango R, et al.
Mol Psychiatry
. 2024 Jul;
30(1):122-130.
PMID: 39003415
Genetics research has potential to alleviate the burden of mental disorders in low- and middle-income-countries through identification of new mechanistic pathways which can lead to efficacious drugs or new drug...
3.
Comparing the effects of CETP in East Asian and European ancestries: a Mendelian randomization study
Dunca D, Chopade S, Gordillo-Maranon M, Hingorani A, Kuchenbaecker K, Finan C, et al.
Nat Commun
. 2024 Jun;
15(1):5302.
PMID: 38906890
CETP inhibitors are a class of lipid-lowering drugs in development for treatment of coronary heart disease (CHD). Genetic studies in East Asian ancestry have interpreted the lack of CETP signal...
4.
Shoham N, Dunca D, Cooper C, Hayes J, McQuillin A, Bass N, et al.
BJPsych Open
. 2024 Apr;
10(3):e73.
PMID: 38563245
No abstract available.
5.
Meng X, Navoly G, Giannakopoulou O, Levey D, Koller D, Pathak G, et al.
Nat Genet
. 2024 Jan;
56(2):222-233.
PMID: 38177345
Most genome-wide association studies (GWAS) of major depression (MD) have been conducted in samples of European ancestry. Here we report a multi-ancestry GWAS of MD, adding data from 21 cohorts...
6.
Wang B, Otten L, Schulze K, Afrah H, Varney L, Cotic M, et al.
Psychol Med
. 2023 Nov;
54(8):1559-1572.
PMID: 37997703
Background: The N100, an early auditory event-related potential, has been found to be altered in patients with psychosis. However, it is unclear if the N100 is a psychosis endophenotype that...
7.
Austin-Zimmerman I, Levey D, Giannakopoulou O, Deak J, Galimberti M, Adhikari K, et al.
Nat Commun
. 2023 Sep;
14(1):6059.
PMID: 37770476
Sleep duration has been linked to a wide range of negative health outcomes and to reduced life expectancy. We present genome-wide association studies of short ( ≤ 5 h) and...
8.
Wang B, Irizar H, Thygesen J, Zartaloudi E, Austin-Zimmerman I, Bhat A, et al.
Schizophr Bull
. 2023 Aug;
49(6):1625-1636.
PMID: 37582581
Background And Hypothesis: Endophenotypes can help to bridge the gap between psychosis and its genetic predispositions, but their underlying mechanisms remain largely unknown. This study aims to identify biological mechanisms...
9.
Martins Custodio H, Clayton L, Bellampalli R, Pagni S, Silvennoinen K, Caswell R, et al.
Brain
. 2023 Apr;
146(9):3885-3897.
PMID: 37006128
Dravet syndrome is an archetypal rare severe epilepsy, considered 'monogenic', typically caused by loss-of-function SCN1A variants. Despite a recognizable core phenotype, its marked phenotypic heterogeneity is incompletely explained by differences...
10.
Shoham N, Dunca D, Cooper C, Hayes J, McQuillin A, Bass N, et al.
BJPsych Open
. 2023 Feb;
9(2):e33.
PMID: 36746515
Background: Increased rates of visual impairment are observed in people with schizophrenia. Aims: We assessed whether genetically predicted poor distance acuity is causally associated with schizophrenia, and whether genetically predicted...