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Karolina Slowicka

Explore the profile of Karolina Slowicka including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 401
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Recent Articles
1.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, et al.
Nat Cancer . 2022 Feb; 1(7):750. PMID: 35122045
No abstract available.
2.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, et al.
Nat Cancer . 2022 Feb; 1(6):620-634. PMID: 35121975
Colorectal cancer (CRC) is highly prevalent in Western society, and increasing evidence indicates strong contributions of environmental factors and the intestinal microbiota to CRC initiation, progression and even metastasis. We...
3.
Catrysse L, Maes B, Mehrotra P, Martens A, Hoste E, Martens L, et al.
Cell Rep . 2021 Sep; 36(12):109748. PMID: 34551300
Obesity-induced inflammation is a major driving force in the development of insulin resistance, type 2 diabetes (T2D), and related metabolic disorders. During obesity, macrophages accumulate in the visceral adipose tissue,...
4.
Picard M, Yonekura S, Slowicka K, Petta I, Rauber C, Routy B, et al.
Cell Death Differ . 2020 Dec; 28(5):1532-1547. PMID: 33262469
Ileal epithelial cell apoptosis and the local microbiota modulate the effects of oxaliplatin against proximal colon cancer by modulating tumor immunosurveillance. Here, we identified an ileal immune profile associated with...
5.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, et al.
Nat Immunol . 2020 Mar; 21(4):381-387. PMID: 32205881
Protein ubiquitination regulates protein stability and modulates the composition of signaling complexes. A20 is a negative regulator of inflammatory signaling, but the molecular mechanisms involved are ill understood. Here, we...
6.
Priem D, Devos M, Druw S, Martens A, Slowicka K, Ting A, et al.
Cell Death Dis . 2020 Jan; 11(1):60. PMID: 31974345
The original version of this article contained an error in the name of one of the co-authors (Wim Declercq). This has been corrected in the PDF and HTML versions.
7.
Priem D, Devos M, Druwe S, Martens A, Slowicka K, Ting A, et al.
Cell Death Dis . 2019 Sep; 10(10):692. PMID: 31534131
The cytokine TNF promotes inflammation either directly by activating the MAPK and NF-κB signaling pathways, or indirectly by triggering cell death. A20 is a potent anti-inflammatory molecule, and mutations in...
8.
Serramito-Gomez I, Boada-Romero E, Slowicka K, Vereecke L, van Loo G, Pimentel-Muinos F
Autophagy . 2019 Jun; 15(9):1657-1659. PMID: 31184523
The C-terminal domain of ATG16L1 includes 7 WD40-type repeats (WD40 domain, WDD) and is not required for canonical macroautophagy/autophagy. Instead, the WDD allows ATG16L1 to induce LC3/Atg8 lipidation in single-membrane...
9.
Slowicka K, Serramito-Gomez I, Boada-Romero E, Martens A, Sze M, Petta I, et al.
Nat Commun . 2019 Apr; 10(1):1834. PMID: 31015422
Prevention of inflammatory bowel disease (IBD) relies on tight control of inflammatory, cell death and autophagic mechanisms, but how these pathways are integrated at the molecular level is still unclear....
10.
Slowicka K, van Loo G
Front Immunol . 2018 Apr; 9:769. PMID: 29692786
Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor. Since then, OPTN has been...