Karol Czubak
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Explore the profile of Karol Czubak including associated specialties, affiliations and a list of published articles.
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10
Citations
188
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Recent Articles
1.
lncRNA DIRC3 regulates invasiveness and insulin-like growth factor signaling in thyroid cancer cells
Wysocki P, Czubak K, Marusiak A, Kolanowska M, Nowis D
Endocr Relat Cancer
. 2023 May;
30(8).
PMID: 37130273
Differentiated thyroid cancers (DTCs) are malignancies that demonstrate strong but largely uncharacterized heritability. Germline variants that influence the risk of DTCs localize in disrupted in renal carcinoma 3 (DIRC3), a...
2.
Czubak K, Sedehizadeh S, Kozlowski P, Wojciechowska M
Int J Mol Sci
. 2019 Sep;
20(18).
PMID: 31500099
Circular RNAs (circRNAs) are a class of single-stranded covalently closed RNA rings. Biogenesis of circRNAs, which may occur co-transcriptionally and post-transcriptionally via a back-splicing mechanism, requires the presence of complementary...
3.
Czubak K, Taylor K, Piasecka A, Sobczak K, Kozlowska K, Philips A, et al.
Front Genet
. 2019 Aug;
10:649.
PMID: 31428124
Splicing aberrations induced as a consequence of the sequestration of muscleblind-like splicing factors on the dystrophia myotonica protein kinase transcript, which contains expanded CUG repeats, present a major pathomechanism of...
4.
Dabrowska M, Czubak K, Juzwa W, Krzyzosiak W, Olejniczak M, Kozlowski P
Nucleic Acids Res
. 2018 Jun;
46(17):e101.
PMID: 29878242
Genome editing technology based on engineered nucleases has been increasingly applied for targeted modification of genes in a variety of cell types and organisms. However, the methods currently used for...
5.
Wojciechowska M, Sobczak K, Kozlowski P, Sedehizadeh S, Wojtkowiak-Szlachcic A, Czubak K, et al.
Sci Rep
. 2018 Apr;
8(1):5885.
PMID: 29651162
Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are human neuromuscular disorders associated with mutations of simple repetitive sequences in affected genes. The abnormal expansion of CTG repeats in...
6.
Klonowska K, Kluzniak W, Rusak B, Jakubowska A, Ratajska M, Krawczynska N, et al.
Oncotarget
. 2017 Nov;
8(44):76357-76374.
PMID: 29100317
, in addition to other members of the gene family, has recently been intensively studied due to its identification as a gene whose activation in cancer is responsible for a...
7.
Klonowska K, Czubak K, Wojciechowska M, Handschuh L, Zmienko A, Figlerowicz M, et al.
Oncotarget
. 2015 Oct;
7(1):176-92.
PMID: 26484415
Somatically acquired genomic alterations that drive oncogenic cellular processes are of great scientific and clinical interest. Since the initiation of large-scale cancer genomic projects (e.g., the Cancer Genome Project, The...
8.
Czubak K, Lewandowska M, Klonowska K, Roszkowski K, Kowalewski J, Figlerowicz M, et al.
Oncotarget
. 2015 Jul;
6(27):23399-416.
PMID: 26156018
A growing body of evidence indicates that miRNAs may be a class of genetic elements that can either drive or suppress oncogenesis. In this study we analyzed the somatic copy...
9.
Klonowska K, Ratajska M, Czubak K, Kuzniacka A, Brozek I, Koczkowska M, et al.
Sci Rep
. 2015 May;
5:10424.
PMID: 25994375
Only approximately 50% of all familial breast cancers can be explained by known genetic factors, including mutations in BRCA1 and BRCA2. One of the most extensively studied candidates for breast...
10.
Lewandowska M, Czubak K, Klonowska K, Jozwicki W, Kowalewski J, Kozlowski P
PLoS One
. 2015 Feb;
10(2):e0117983.
PMID: 25719557
Lung cancer is the leading cause of cancer-related death worldwide. Recent progress in lung cancer diagnosis and treatment has been achieved due to a better understanding the molecular mechanisms of...