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Karlien Van Wesemael

Explore the profile of Karlien Van Wesemael including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 96
Followers 0
Related Specialties
General Medicine
Science
Biology
Top 10 Co-Authors
Guy Haegeman
Jan Tavernier
Sarah Gerlo
Krzysztof Kolmus
Karolien De Bosscher
Dorien Clarisse
Fritz Offner
Jonathan Thommis
Christophe Ampe
Marleen Van Troys
Published In
PLoS One
Mol Cell Biol
Oncotarget
J Biomed Biotechnol
Cell Mol Life Sci
Affiliations
Soon will be listed here.
Recent Articles
1.
Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
Clarisse D, Prekovic S, Vlummens P, Staessens E, Van Wesemael K, Thommis J, et al.
Cell Mol Life Sci . 2023 Aug; 80(9):249. PMID: 37578563
The glucocorticoid receptor (GR) is a crucial drug target in multiple myeloma as its activation with glucocorticoids effectively triggers myeloma cell death. However, as high-dose glucocorticoids are also associated with...
2.
Correction: β-Agonists Selectively Modulate Proinflammatory Gene Expression in Skeletal Muscle Cells via Non-Canonical Nuclear Crosstalk Mechanisms
Kolmus K, Van Troys M, Van Wesemael K, Ampe C, Haegeman G, Tavernier J, et al.
PLoS One . 2023 Jun; 18(6):e0287938. PMID: 37368923
[This corrects the article DOI: 10.1371/journal.pone.0090649.].
3.
Effect of combining glucocorticoids with Compound A on glucocorticoid receptor responsiveness in lymphoid malignancies
Clarisse D, Van Wesemael K, Tavernier J, Offner F, Beck I, De Bosscher K
PLoS One . 2018 May; 13(5):e0197000. PMID: 29738549
Glucocorticoids (GCs) are a cornerstone in the treatment of lymphoid malignancies such as multiple myeloma (MM) and acute lymphoblastic leukemia (ALL). Yet, prolonged GC use is hampered by deleterious GC-related...
4.
Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies
Clarisse D, Thommis J, Van Wesemael K, Houtman R, Ratman D, Tavernier J, et al.
Oncotarget . 2018 Jan; 8(65):109675-109691. PMID: 29312638
Coregulators cooperate with nuclear receptors, such as the glucocorticoid receptor (GR), to enhance or repress transcription. These regulatory proteins are implicated in cancer, yet, their role in lymphoid malignancies, including...
5.
β-agonists selectively modulate proinflammatory gene expression in skeletal muscle cells via non-canonical nuclear crosstalk mechanisms
Kolmus K, Van Troys M, Van Wesemael K, Ampe C, Haegeman G, Tavernier J, et al.
PLoS One . 2014 Mar; 9(6):e90649. PMID: 24603712
The proinflammatory cytokine Tumour Necrosis Factor (TNF)-α is implicated in a variety of skeletal muscle pathologies. Here, we have investigated how in vitro cotreatment of skeletal muscle C2C12 cells with...
6.
Hunting for serine 276-phosphorylated p65
Spooren A, Kolmus K, Vermeulen L, Van Wesemael K, Haegeman G, Gerlo S
J Biomed Biotechnol . 2010 Mar; 2010:275892. PMID: 20204068
The transcription factor nuclear factor kappaB (NF-kappaB) is one of the central mediators of inflammatory gene expression. Several posttranslational modifications of NF-kappaB, regulating its transactivation ability, have been described. Especially...
7.
Hyperactivated NF-{kappa}B and AP-1 transcription factors promote highly accessible chromatin and constitutive transcription across the interleukin-6 gene promoter in metastatic breast cancer cells
Ndlovu M, Van Lint C, Van Wesemael K, Callebert P, Chalbos D, Haegeman G, et al.
Mol Cell Biol . 2009 Aug; 29(20):5488-504. PMID: 19687301
Interleukin-6 (IL-6), involved in cancer-related inflammation, acts as an autocrine and paracrine growth factor, which promotes angiogenesis, metastasis, and subversion of immunity, and changes the response to hormones and to...