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Karlien Van Wesemael

Explore the profile of Karlien Van Wesemael including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Clarisse D, Prekovic S, Vlummens P, Staessens E, Van Wesemael K, Thommis J, et al.
Cell Mol Life Sci . 2023 Aug; 80(9):249. PMID: 37578563
The glucocorticoid receptor (GR) is a crucial drug target in multiple myeloma as its activation with glucocorticoids effectively triggers myeloma cell death. However, as high-dose glucocorticoids are also associated with...
2.
Kolmus K, Van Troys M, Van Wesemael K, Ampe C, Haegeman G, Tavernier J, et al.
PLoS One . 2023 Jun; 18(6):e0287938. PMID: 37368923
[This corrects the article DOI: 10.1371/journal.pone.0090649.].
3.
Clarisse D, Van Wesemael K, Tavernier J, Offner F, Beck I, De Bosscher K
PLoS One . 2018 May; 13(5):e0197000. PMID: 29738549
Glucocorticoids (GCs) are a cornerstone in the treatment of lymphoid malignancies such as multiple myeloma (MM) and acute lymphoblastic leukemia (ALL). Yet, prolonged GC use is hampered by deleterious GC-related...
4.
Clarisse D, Thommis J, Van Wesemael K, Houtman R, Ratman D, Tavernier J, et al.
Oncotarget . 2018 Jan; 8(65):109675-109691. PMID: 29312638
Coregulators cooperate with nuclear receptors, such as the glucocorticoid receptor (GR), to enhance or repress transcription. These regulatory proteins are implicated in cancer, yet, their role in lymphoid malignancies, including...
5.
Kolmus K, Van Troys M, Van Wesemael K, Ampe C, Haegeman G, Tavernier J, et al.
PLoS One . 2014 Mar; 9(6):e90649. PMID: 24603712
The proinflammatory cytokine Tumour Necrosis Factor (TNF)-α is implicated in a variety of skeletal muscle pathologies. Here, we have investigated how in vitro cotreatment of skeletal muscle C2C12 cells with...
6.
Spooren A, Kolmus K, Vermeulen L, Van Wesemael K, Haegeman G, Gerlo S
J Biomed Biotechnol . 2010 Mar; 2010:275892. PMID: 20204068
The transcription factor nuclear factor kappaB (NF-kappaB) is one of the central mediators of inflammatory gene expression. Several posttranslational modifications of NF-kappaB, regulating its transactivation ability, have been described. Especially...
7.
Ndlovu M, Van Lint C, Van Wesemael K, Callebert P, Chalbos D, Haegeman G, et al.
Mol Cell Biol . 2009 Aug; 29(20):5488-504. PMID: 19687301
Interleukin-6 (IL-6), involved in cancer-related inflammation, acts as an autocrine and paracrine growth factor, which promotes angiogenesis, metastasis, and subversion of immunity, and changes the response to hormones and to...