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Karlen Lyons-Ruth

Explore the profile of Karlen Lyons-Ruth including associated specialties, affiliations and a list of published articles. Areas
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Articles 82
Citations 1708
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Recent Articles
1.
Fleming L, Ohashi K, Bosquet Enlow M, Khoury J, Klengel T, Lyons-Ruth K, et al.
bioRxiv . 2025 Jan; PMID: 39868254
Importance: Childhood maltreatment (CM) is associated with the early onset of psychiatric and medical disorders and accelerated biological aging. Objective: To identify types of maltreatment and developmental sensitive periods that...
2.
Lyons-Ruth K, Chasson M, Khoury J, Ahtam B
Neurosci Biobehav Rev . 2024 Jun; 163:105746. PMID: 38838878
Early life stress has been associated with elevated risk for later psychopathology. One mechanism that may contribute to such long-term risk is alterations in amygdala development, a brain region critical...
3.
Eirich R, Pador P, Watt J, Racine N, Lyons-Ruth K, Madigan S
Infant Ment Health J . 2024 May; 45(4):438-448. PMID: 38780376
Community agencies and practitioners around the globe seek opportunities to learn various assessment tools and interventions rooted in attachment theory. However, information regarding the feasibility of implementation and sustainability of...
4.
Stender S, Davidsen K, Lyons-Ruth K, Harder S
Personal Disord . 2024 Feb; 15(3):207-212. PMID: 38330355
Disinhibited attachment behavior (DAB) among infants is persistent and associated with behavioral and relational problems throughout childhood and adolescence. Little is known about risk factors for DAB among infants reared...
5.
Nystrom-Hansen M, Andersen M, Davidsen K, Roehder K, Trier C, Nayberg E, et al.
Arch Womens Ment Health . 2024 Feb; 27(4):577-584. PMID: 38308143
Purpose: Maternal cortisol levels in pregnancy may support the growth of or adversely affect fetal organs, including the brain. While moderate cortisol levels are essential for fetal development, excessive or...
6.
Khoury J, Ahtam B, Ou Y, Jenkins E, Klengel T, Bosquet Enlow M, et al.
Psychoneuroendocrinology . 2023 Sep; 158:106379. PMID: 37683305
Despite a large animal literature documenting the role of low maternal nurturance and elevated glucocorticoid production on offspring limbic development, these pathways have not yet been assessed during human infancy....
7.
Lyons-Ruth K, Ahtam B, Li F, Dickerman S, Khoury J, Sisitsky M, et al.
Hum Brain Mapp . 2023 Jul; 44(12):4572-4589. PMID: 37417795
Distinct neural effects of threat versus deprivation emerge by childhood, but little data are available in infancy. Withdrawn versus negative parenting may represent dimensionalized indices of early deprivation versus early...
8.
Lyons-Ruth K, Li F, Khoury J, Ahtam B, Sisitsky M, Ou Y, et al.
Res Child Adolesc Psychopathol . 2023 May; 51(12):1919-1932. PMID: 37160577
Severity of maternal childhood maltreatment has been associated with lower infant grey matter volume and amygdala volume during the first two years of life. A developing literature argues that effects...
9.
Wells J, Knoll M, Lyons-Ruth K, Obsuth I
Child Abuse Negl . 2023 Apr; 140:106190. PMID: 37060688
Background: Hostile-Helpless (HH) state of mind is a form of disorganised attachment that is strongly associated with prior experiences of abuse. However, how abuse experiences contribute toward HH states of...
10.
Penner F, Khoury J, Bosquet Enlow M, Lyons-Ruth K
Child Abuse Negl . 2023 Mar; 139:106107. PMID: 36870268
Background: The negative effects of childhood maltreatment can be intergenerational, and the prenatal period may play an important role in this intergenerational transmission. Maternal hypothalamic-pituitary-adrenal (HPA) axis dysfunction and maternal...