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Karin Hollberg

Explore the profile of Karin Hollberg including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 117
Followers 0
Related Specialties
Endocrinology
Cell Biology
Orthopedics
Top 10 Co-Authors
Goran Andersson
Maria Norgard
Barbro Ek-Rylander
Pernilla Lang
Kjell Hultenby
Jenny Ljusberg
Tobias Larsson
Riku Kiviranta
Kenneth B Jonsson
Alison Hayman
Published In
Bone
Exp Cell Res
J Bone Miner Res
Cells Tissues Organs
J Bone Miner Metab
Affiliations
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Recent Articles
1.
Transgenic overexpression of tartrate-resistant acid phosphatase is associated with induction of osteoblast gene expression and increased cortical bone mineral content and density
Gradin P, Hollberg K, Cassady A, Lang P, Andersson G
Cells Tissues Organs . 2012 Jan; 196(1):68-81. PMID: 22248481
Bone remodeling is a central event in the maintenance of skeletal tissue, and involves cycles of resorption followed by the formation of bone tissue. The activity of osteoclasts and osteoblasts...
2.
Osteoclast polarization is not required for degradation of bone matrix in rachitic FGF23 transgenic mice
Hollberg K, Marsell R, Norgard M, Larsson T, Jonsson K, Andersson G
Bone . 2008 Mar; 42(6):1111-21. PMID: 18346951
Hypophosphatemic transgenic (tg) mice overexpressing FGF23 in osteoblasts display disorganized growth plates and reduced bone mineral density characteristic of rickets/osteomalacia. These FGF23 tg mice were used as an in vivo...
3.
Proteolytic processing and polarized secretion of tartrate-resistant acid phosphatase is altered in a subpopulation of metaphyseal osteoclasts in cathepsin K-deficient mice
Zenger S, Hollberg K, Ljusberg J, Norgard M, Ek-Rylander B, Kiviranta R, et al.
Bone . 2007 Sep; 41(5):820-32. PMID: 17765026
Tartrate-resistant acid phosphatase (TRAP) is an enzyme highly expressed in osteoclasts and thought to participate in osteoclast-mediated bone turnover. Cathepsin K (Ctsk) is the major collagenolytic cysteine proteinase expressed in...
4.
Polarization and secretion of cathepsin K precede tartrate-resistant acid phosphatase secretion to the ruffled border area during the activation of matrix-resorbing clasts
Hollberg K, Nordahl J, Hultenby K, Mengarelli-Widholm S, Andersson G, Reinholt F
J Bone Miner Metab . 2005 Nov; 23(6):441-9. PMID: 16261450
The activation sequence of clasts (the designation clast was used because ultrastructurally in this tissue, it is not always possible to differentiate between chondroclasts sitting on cartilage and osteoclasts sitting...
5.
TRACP as an osteopontin phosphatase
Andersson G, Ek-Rylander B, Hollberg K, Ljusberg-Sjolander J, Lang P, Norgard M, et al.
J Bone Miner Res . 2003 Oct; 18(10):1912-5. PMID: 14584906
TRACP is synthesized as a latent proenzyme requiring proteolytic processing to attain maximal phosphatase activity. Excision of an exposed loop domain abolishes the interaction between the loop residue Asp146 and...
6.
Osteoclasts from mice deficient in tartrate-resistant acid phosphatase have altered ruffled borders and disturbed intracellular vesicular transport
Hollberg K, Hultenby K, Hayman A, Cox T, Andersson G
Exp Cell Res . 2002 Sep; 279(2):227-38. PMID: 12243748
Tartrate-resistant acid phosphatase (TRAP) is an enzyme highly expressed in osteoclasts (OC) and chondroclasts. As an approach to pinpoint the function of TRAP in bone-resorbing osteoclasts, the morphological phenotypic alterations...