Karin Heurlier
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Explore the profile of Karin Heurlier including associated specialties, affiliations and a list of published articles.
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11
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885
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Recent Articles
1.
Crepin A, Barbey C, Beury-Cirou A, Helias V, Taupin L, Reverchon S, et al.
PLoS One
. 2012 Apr;
7(4):e35176.
PMID: 22539957
Background: Several small diffusible molecules are involved in bacterial quorum sensing and virulence. The production of autoinducers-1 and -2, quinolone, indole and γ-amino butyrate signaling molecules was investigated in a...
2.
Lee D, Bingle L, Heurlier K, Pallen M, Penn C, Busby S, et al.
BMC Microbiol
. 2009 Dec;
9:252.
PMID: 20003185
Background: Homologous recombination mediated by the lambda-Red genes is a common method for making chromosomal modifications in Escherichia coli. Several protocols have been developed that differ in the mechanisms by...
3.
Heurlier K, Vendeville A, Halliday N, Green A, Winzer K, Tang C, et al.
J Bacteriol
. 2008 Dec;
191(4):1293-302.
PMID: 19074394
The activated methyl cycle (AMC) is a central metabolic pathway used to generate (and recycle) several important metabolites and enable methylation. Pfs and LuxS are considered integral components of this...
4.
Establishing bacterial communities by 'word of mouth': LuxS and autoinducer 2 in biofilm development
Hardie K, Heurlier K
Nat Rev Microbiol
. 2008 Jun;
6(8):635-43.
PMID: 18536728
Multicellular bacterial communities (biofilms) abound in nature, and their successful formation and survival is likely to require cell-cell communication--including quorum sensing--to co-ordinate appropriate gene expression. The only mode of quorum...
5.
Heurlier K, Thomson M, Aziz N, Moir J
J Bacteriol
. 2008 Feb;
190(7):2488-95.
PMID: 18245279
We have analyzed the extent of regulation by the nitric oxide (NO)-sensitive repressor NsrR from Neisseria meningitidis MC58, using microarray analysis. Target genes that appeared to be regulated by NsrR,...
6.
Heurlier K, Denervaud V, Haas D
Int J Med Microbiol
. 2006 Mar;
296(2-3):93-102.
PMID: 16503417
In Pseudomonas aeruginosa, cell-cell communication based on N-acyl-homoserine lactone (AHL) signal molecules (termed quorum sensing) is known to control the production of extracellular virulence factors. Hence, in pathogenic interactions with...
7.
Heurlier K, Denervaud V, Haenni M, Guy L, Krishnapillai V, Haas D
J Bacteriol
. 2005 Jul;
187(14):4875-83.
PMID: 15995202
In Pseudomonas aeruginosa, N-acylhomoserine lactone signals regulate the expression of several hundreds of genes, via the transcriptional regulator LasR and, in part, also via the subordinate regulator RhlR. This regulatory...
8.
Vendeville A, Winzer K, Heurlier K, Tang C, Hardie K
Nat Rev Microbiol
. 2005 May;
3(5):383-96.
PMID: 15864263
Bacteria exploit many mechanisms to communicate with each other and their surroundings. Mechanisms using small diffusible signals to coordinate behaviour with cell density (quorum sensing) frequently contribute to pathogenicity. However,...
9.
Heurlier K, Williams F, Heeb S, Dormond C, Pessi G, Singer D, et al.
J Bacteriol
. 2004 May;
186(10):2936-45.
PMID: 15126453
In Pseudomonas aeruginosa, the small RNA-binding, regulatory protein RsmA is a negative control element in the formation of several extracellular products (e.g., pyocyanin, hydrogen cyanide, PA-IL lectin) as well as...
10.
Heurlier K, Denervaud V, Pessi G, Reimmann C, Haas D
J Bacteriol
. 2003 Mar;
185(7):2227-35.
PMID: 12644493
In Pseudomonas aeruginosa PAO1, the expression of several virulence factors such as elastase, rhamnolipids, and hydrogen cyanide depends on quorum-sensing regulation, which involves the lasRI and rhlRI systems controlled by...