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Karim I Sallam

Explore the profile of Karim I Sallam including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 197
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Recent Articles
1.
Kim D, Chu E, Keamy-Minor E, Paranjpe I, Tang W, OSullivan J, et al.
Front Cardiovasc Med . 2024 Sep; 11:1429230. PMID: 39314763
Mavacamten is a first-in-class cardiac myosin ATPase inhibitor, approved by the United States Food and Drug Administration for the treatment of hypertrophic cardiomyopathy with obstructive physiology (oHCM). Here, we present...
2.
Pan S, Sommese R, Sallam K, Nag S, Sutton S, Miller S, et al.
BMC Med Genet . 2015 Oct; 16:97. PMID: 26498512
Background: As next generation sequencing for the genetic diagnosis of cardiovascular disorders becomes more widely used, establishing causality for putative disease causing variants becomes increasingly relevant. Diseases of the cardiac...
3.
Wu H, Lee J, Vincent L, Wang Q, Gu M, Lan F, et al.
Cell Stem Cell . 2015 Jun; 17(1):89-100. PMID: 26095046
β-adrenergic signaling pathways mediate key aspects of cardiac function. Its dysregulation is associated with a range of cardiac diseases, including dilated cardiomyopathy (DCM). Previously, we established an iPSC model of...
4.
Sharma A, Marceau C, Hamaguchi R, Burridge P, Rajarajan K, Churko J, et al.
Circ Res . 2014 Jul; 115(6):556-66. PMID: 25015077
Rationale: Viral myocarditis is a life-threatening illness that may lead to heart failure or cardiac arrhythmias. A major causative agent for viral myocarditis is the B3 strain of coxsackievirus, a...