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Kari Antero Makela

Explore the profile of Kari Antero Makela including associated specialties, affiliations and a list of published articles. Areas
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Citations 44
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Recent Articles
1.
Stenback V, Lehtonen I, Makela K, Raza G, Ylinen V, Valtonen R, et al.
Int J Mol Sci . 2024 Sep; 25(17). PMID: 39273084
Massage therapy increases muscle blood flow and heat, relieving pain, improving immune function, and increasing vagal activity. The mechanisms are unclear. Muscles release cytokines and other peptides called myokines. These...
2.
Nikkola A, Makela K, Herzig K, Mutt S, Prasannan A, Seppanen H, et al.
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555366
Only 3-5% of heavy alcohol users develop acute alcohol pancreatitis (AAP). This suggests that additional triggers are required to initiate the inflammatory process. Genetic susceptibility contributes to the development of...
3.
Saarinen M, Karkkainen O, Hanhineva K, Tiihonen K, Hibberd A, Makela K, et al.
Sci Rep . 2020 Dec; 10(1):21577. PMID: 33299048
Polydextrose (PDX) is a branched glucose polymer, utilized as a soluble dietary fiber. Recently, PDX was found to have hypolipidemic effects and effects on the gut microbiota. To investigate these...
4.
Makela K, Leppaluoto J, Jokelainen J, Jamsa T, Keinanen-Kiukaanniemi S, Herzig K
Front Physiol . 2019 May; 10:456. PMID: 31114503
Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a liver serine protease regulating LDL cholesterol metabolism. PCSK9 binds to LDL receptors and guides them to lysosomes for degradation, thus increasing...
5.
Raza G, Putaala H, Hibberd A, Alhoniemi E, Tiihonen K, Makela K, et al.
Sci Rep . 2017 Jul; 7(1):5294. PMID: 28706193
Obesity and dyslipidemia are hallmarks of metabolic and cardiovascular diseases. Polydextrose (PDX), a soluble fiber has lipid lowering effects. We hypothesize that PDX reduces triglycerides and cholesterol by influencing gut...