Karen Sermon
Overview
Explore the profile of Karen Sermon including associated specialties, affiliations and a list of published articles.
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75
Citations
1705
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Recent Articles
11.
Verpoest W, Okutman O, Van Der Kelen A, Sermon K, Viville S
Hum Reprod
. 2023 Oct;
38(12):2289-2295.
PMID: 37801292
The field of reproductive genetics has undergone significant advancements with the completion of the Human Genome Project and the development of high-throughput sequencing techniques. This has led to the identification...
12.
Regin M, Essahib W, Demtschenko A, Dewandre D, David L, Gerri C, et al.
Hum Reprod
. 2023 Jun;
38(8):1484-1498.
PMID: 37295962
Study Question: Which processes and transcription factors specify the first and second lineage segregation events during human preimplantation development? Summary Answer: Differentiation into trophectoderm (TE) cells can be initiated independently...
13.
Makieva S, Fraire-Zamora J, Mincheva M, Uraji J, Ali Z, Ammar O, et al.
Hum Reprod
. 2022 Dec;
38(2):324-327.
PMID: 36583604
No abstract available.
14.
Van Der Kelen A, Okutman O, Javey E, Serdarogullari M, Janssens C, Ghosh M, et al.
Hum Reprod Update
. 2022 Dec;
29(2):218-232.
PMID: 36571510
Background: As in other domains of medicine, high-throughput sequencing methods have led to the identification of an ever-increasing number of gene variants in the fields of both male and female...
15.
De Rycke M, Capalbo A, Coonen E, Coticchio G, Fiorentino F, Goossens V, et al.
Hum Reprod Open
. 2022 Nov;
2022(4):hoac044.
PMID: 36349144
Study Question: How should ART/preimplantation genetic testing (PGT) centres manage the detection of chromosomal mosaicism following PGT? Summary Answer: Thirty good practice recommendations were formulated that can be used by...
16.
Regin M, Spits C, Sermon K
Mol Hum Reprod
. 2022 Apr;
28(4).
PMID: 35404421
About 8 out of 10 human embryos obtained in vitro harbour chromosomal abnormalities of either meiotic or mitotic origin. Abnormalities of mitotic origin lead to chromosomal mosaicism, a phenomenon that...
17.
Mertens J, Regin M, De Munck N, Couvreu de Deckersberg E, Belva F, Sermon K, et al.
Hum Mol Genet
. 2022 Mar;
31(21):3629-3642.
PMID: 35285472
Humans present remarkable diversity in their mitochondrial DNA (mtDNA) in terms of variants across individuals as well as across tissues and even cells within one person. We have investigated the...
18.
Maia N, Potelle S, Yildirim H, Duvet S, Akula S, Schulz C, et al.
Am J Hum Genet
. 2022 Jan;
109(2):345-360.
PMID: 35045343
Free oligosaccharides (fOSs) are soluble oligosaccharide species generated during N-glycosylation of proteins. Although little is known about fOS metabolism, the recent identification of NGLY1 deficiency, a congenital disorder of deglycosylation...
19.
Dziedzicka D, Tewary M, Keller A, Tilleman L, Prochazka L, Ostblom J, et al.
Sci Rep
. 2021 Mar;
11(1):6137.
PMID: 33731744
Low differentiation propensity towards a targeted lineage can significantly hamper the utility of individual human pluripotent stem cell (hPSC) lines in biomedical applications. Here, we use monolayer and micropatterned cell...
20.
Mertens J, Zambelli F, Daneels D, Caljon B, Sermon K, Spits C
Bio Protoc
. 2021 Mar;
9(13):e3283.
PMID: 33654798
Detecting heteroplasmies in the mitochondrial DNA (mtDNA) has been a challenge for many years. In the past, Sanger sequencing was the main option to perform this analysis, however, this method...