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Karen Savage

Explore the profile of Karen Savage including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 293
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Recent Articles
1.
Savage K, Sarris J, Hughes M, Bousman C, Rossell S, Scholey A, et al.
Nutrients . 2023 Nov; 15(21). PMID: 37960239
Generalised Anxiety Disorder (GAD) is a prevalent, chronic mental health disorder. The measurement of regional brain gamma-aminobutyric acid (GABA) offers insight into its role in anxiety and is a potential...
2.
Keegan A, Savage K, Bousman C, Nolidin K, Cribb L, Pipingas A, et al.
Behav Brain Res . 2023 Nov; 458:114756. PMID: 37951418
Inflammation is repressed by interleukin 10 (IL10), a potent anti-inflammatory cytokine, and unchecked inflammation can have detrimental effects on cognition. In healthy older adults enrolled in the Australian Research Council...
3.
Savage K, Porter C, Bunnett E, Hana M, Keegan A, Ogden E, et al.
Exp Gerontol . 2023 Apr; 177:112186. PMID: 37105503
Introduction: Early identification and management of physical and mental illness is vital to maintain quality of life as we age. Markers of peripheral inflammation and liver function show elevations with...
4.
Savage K, Gogarty L, Lea A, Deleuil S, Nolidin K, Croft K, et al.
Antioxidants (Basel) . 2022 May; 11(5). PMID: 35624687
The increasing proportion of older citizens in our society reflects a need to better understand age-related biological underpinnings of mood, as depression in older age may be under-diagnosed. Pre-clinical and...
5.
Komanduri M, Savage K, Lea A, McPhee G, Nolidin K, Deleuil S, et al.
Nutrients . 2022 Jan; 14(1). PMID: 35010939
Ageing is associated with changes in biological processes, including reductions in cognitive functions and gut microbiome diversity. However, not much is known about the relationship between cognition and the microbiome...
6.
Parmenter B, Croft K, Cribb L, Cooke M, Bondonno C, Lea A, et al.
Br J Nutr . 2021 Aug; 128(2):279-289. PMID: 34423750
Flavonoids have shown anti-hypertensive and anti-atherosclerotic properties: the impact of habitual flavonoid intake on vascular function, central haemodynamics and arterial stiffness may be important. We investigated the relationship between habitual...
7.
Savage K, Kingshott D, Gubko A, Thee A, Burjawi T, Croft K, et al.
Exp Aging Res . 2021 Feb; 47(4):322-346. PMID: 33616006
F-Isoprostanes are putative markers of oxidative stress, one of the processes associated with biological senescence. Evidence exists for elevated F-Isoprostanes in chronic conditions including psychiatric disorders. Few studies have examined...
8.
Petrov K, Hayley A, Catchlove S, Savage K, Stough C
Mech Ageing Dev . 2020 Oct; 192:111388. PMID: 33080282
Objective: Examine subjective sleep quality and inflammation among healthy older adults participating in the Australian Research Council Longevity Intervention (ARCLI). Methods: Data was taken from a sub-set of 232 participants...
9.
White D, Camfield D, Ossoukhova A, Savage K, Cozannet R, Fanca-Berthon P, et al.
Hum Psychopharmacol . 2020 Sep; 35(6):1-6. PMID: 32896022
Objective: To investigate the effects of acute Panax quinquefolius (American ginseng) administration on steady state visually evoked potentials (SSVEPs) during completion of working memory and continuous performance tasks. Methods: A...
10.
Sarris J, Murphy J, Stough C, Mischoulon D, Bousman C, Macdonald P, et al.
Psychopharmacology (Berl) . 2019 Nov; 237(1):209-218. PMID: 31712971
Rationale: Dysregulation of the one carbon cycle is documented in depression. Thereby, S-adenosylmethionine (SAMe), a one-carbon cycle nutraceutical compound with a favourable side effect profile, has a theoretical rationale for...