Karen P Alexander
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Explore the profile of Karen P Alexander including associated specialties, affiliations and a list of published articles.
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256
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8228
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Recent Articles
1.
Reynolds H, Page C, Shaw L, Berman D, Chaitman B, Picard M, et al.
Circ Cardiovasc Interv
. 2024 Dec;
17(12):e013743.
PMID: 39689188
Background: The relationship between the extent and severity of stress-induced ischemia and the extent and severity of anatomic coronary artery disease (CAD) in patients with obstructive CAD is multifactorial and...
2.
Krychtiuk K, Lopes R, Wojdyla D, Goodman S, Aronson R, Windecker S, et al.
JACC Adv
. 2024 Nov;
3(11):101335.
PMID: 39493312
Background: Patients with atrial fibrillation (AF) after an acute coronary syndrome (ACS) and/or undergoing percutaneous coronary intervention (PCI) with multiple comorbidities are at increased risk for bleeding and ischemic events....
3.
Kuno T, Weisz G, Genereux P, Claessen B, Shechter M, Alexander K, et al.
Catheter Cardiovasc Interv
. 2024 Jul;
104(3):483-491.
PMID: 39007455
Background: Incomplete revascularization (ICR) after percutaneous coronary intervention (PCI) is associated with mortality and morbidity. Aim: We sought to investigate whether ICR in the left anterior descending artery (LAD) is...
4.
Guimaraes P, Lopes R, Wojdyla D, Alexander J, Goodman S, Aronson R, et al.
Am J Med
. 2024 Jun;
137(10):958-965.
PMID: 38876331
Objective: We aimed to evaluate the safety and efficacy of antithrombotic strategies by age in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention in AUGUSTUS. Methods:...
5.
6.
Reynolds H, Cyr D, Merz C, Shaw L, Chaitman B, Boden W, et al.
J Am Heart Assoc
. 2024 Feb;
13(5):e029850.
PMID: 38410945
Background: Women with chronic coronary disease are generally older than men and have more comorbidities but less atherosclerosis. We explored sex differences in revascularization, guideline-directed medical therapy, and outcomes among...
7.
Krychtiuk K, Marquis-Gravel G, Murphy S, Alexander K, Chiswell K, Green J, et al.
Eur Heart J Cardiovasc Pharmacother
. 2024 Jan;
10(4):279-288.
PMID: 38271596
Aims: Large outcome trials have demonstrated cardiovascular benefits of selected glucagon-like peptide-1 (GLP-1) receptor agonists. We examined coronary disease outcomes in the Harmony Outcomes trial of the GLP-1 receptor agonist...
8.
Orkaby A, Lu B, Ho Y, Treu T, Galloway A, Wilson P, et al.
J Am Geriatr Soc
. 2023 Dec;
72(2):410-422.
PMID: 38055194
Background: Statins are part of long-term medical regimens for many older adults. Whether frailty modifies the protective relationship between statins, mortality, and major adverse cardiovascular events (MACE) is unknown. Methods:...
9.
Goyal P, Kwak M, Al Malouf C, Kumar M, Rohant N, Damluji A, et al.
JACC Adv
. 2023 Sep;
1(3).
PMID: 37705890
Older adults with cardiovascular disease (CVD) contend with deficits across multiple domains of health due to age-related physiological changes and the impact of CVD. Multimorbidity, polypharmacy, cognitive changes, and diminished...
10.
Kumar M, Orkaby A, Tighe C, Villareal D, Billingsley H, Nanna M, et al.
JACC Adv
. 2023 Sep;
2(7).
PMID: 37664644
The population worldwide is getting older as a result of advances in public health, medicine, and technology. Older individuals are living longer with a higher prevalence of subclinical and clinical...