Karen N Thatcher
Overview
Explore the profile of Karen N Thatcher including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
315
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wang N, Parokonny A, Thatcher K, Driscoll J, Malone B, Dorrani N, et al.
BMC Genet
. 2008 Jan;
9:2.
PMID: 18177502
Background: Maternally-derived duplications that include the imprinted region on the proximal long arm of chromosome 15 underlie a complex neurobehavioral disorder characterized by cognitive impairment, seizures and a substantial risk...
2.
Yasui D, Peddada S, Bieda M, Vallero R, Hogart A, Nagarajan R, et al.
Proc Natl Acad Sci U S A
. 2007 Nov;
104(49):19416-21.
PMID: 18042715
Mutations in MECP2 cause the autism-spectrum disorder Rett syndrome. MeCP2 is predicted to bind to methylated promoters and silence transcription. However, the first large-scale mapping of neuronal MeCP2-binding sites on...
3.
Thatcher K, LaSalle J
Epigenetics
. 2007 Apr;
1(1):24-31.
PMID: 17464364
Mutations within the gene encoding methyl CpG binding protein 2 (MECP2) cause the autism-spectrum neurodevelopmental disorder Rett Syndrome (RTT). MECP2 recruits histone deacetylase to methylated DNA and acts as a...
4.
Delgado I, Kim D, Thatcher K, LaSalle J, Van den Veyver I
BMC Med Genet
. 2006 Jul;
7:61.
PMID: 16859563
Background: More than 85% of Rett syndrome (RTT) patients have heterozygous mutations in the X-linked MECP2 gene which encodes methyl-CpG-binding protein 2, a transcriptional repressor that binds methylated CpG sites....
5.
LaSalle J, Hogart A, Thatcher K
Int Rev Neurobiol
. 2006 Mar;
71:131-65.
PMID: 16512349
No abstract available.
6.
Thatcher K, Peddada S, Yasui D, LaSalle J
Hum Mol Genet
. 2005 Feb;
14(6):785-97.
PMID: 15689352
Rett syndrome (RTT), caused by mutations in MECP2 (encoding methyl CpG binding protein 2), and Angelman syndrome (AS), caused by maternal deficiency of chromosome 15q11-13, are autism-spectrum neurodevelopmental disorders. MeCP2...