Karen Lai
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Explore the profile of Karen Lai including associated specialties, affiliations and a list of published articles.
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10
Citations
493
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Recent Articles
1.
van Boxel E, Rahman S, Lai K, Boulos N, Davis N
Arch Dis Child
. 2024 Mar;
109(10):822-825.
PMID: 38471743
Objective: To assess efficacy and tolerability of semaglutide as a weight loss treatment for children living with comorbid obesity. Design: Retrospective observational study of the first 50 children from a...
2.
Ghosh A, Thapa R, Hariani H, Volyanyuk M, Ogle S, Orloff K, et al.
Pharmaceutics
. 2021 Sep;
13(9).
PMID: 34575438
Oxidative stress is a known contributor to the progression of dry eye disease pathophysiology, and previous studies have shown that antioxidant intervention is a promising therapeutic approach to reduce the...
3.
Norrie J, Nityanandam A, Lai K, Chen X, Wilson M, Stewart E, et al.
Nat Commun
. 2021 Jul;
12(1):4535.
PMID: 34315877
Retinoblastoma is a childhood cancer of the developing retina that initiates with biallelic inactivation of the RB1 gene. Children with germline mutations in RB1 have a high likelihood of developing...
4.
Donaldson K, Roach B, Ford J, Lai K, Sreenivasan K, Mathalon D
Biol Psychol
. 2018 Nov;
140:9-18.
PMID: 30428312
The error-related negativity (ERN) and error-positivity (Pe) are commonly linked to error-detection and strategic processing. Studies have documented the influence of conflict probability on ERN amplitude. However, the influence of...
5.
Hough C, Luks T, Lai K, Vigil O, Guillory S, Nongpiur A, et al.
Psychiatry Res Neuroimaging
. 2016 Aug;
255:50-9.
PMID: 27522332
We examined differences in regional brain activation during tests of executive function in individuals with Hoarding Disorder (HD), Obsessive Compulsive Disorder (OCD), and healthy controls (HC) using functional magnetic resonance...
6.
Lai K, Guo S, Ijadi-Maghsoodi R, Puffer M, Kataoka S
Psychiatr Serv
. 2016 Jul;
67(12):1328-1333.
PMID: 27417895
Objective: School-based health centers (SBHCs) reduce access barriers to mental health care and improve educational outcomes for youths. This qualitative study evaluated the innovations and challenges of a unique network...
7.
Chandra P, Lai K, Sung H, Murthy N, Kohn J
Biointerphases
. 2010 Sep;
5(2):53-9.
PMID: 20831349
Textured surfaces obtained by UV laser ablation of poly(ethylene terephthalate) films were used to study the effect of shape and spacing of surface features on cellular response. Two distinct patterns,...
8.
Chan A, Ma B, Lo Y, Leung S, Kwan W, Hui E, et al.
J Clin Oncol
. 2004 Jul;
22(15):3053-60.
PMID: 15284255
Purpose: To assess the efficacy of neoadjuvant paclitaxel and carboplatin (TC) followed by concurrent cisplatin and radiotherapy (RT) in patients with locoregionally advanced nasopharyngeal carcinoma (NPC) and to monitor treatment...
9.
Lai K, Robertson M, Schaffer D
Biophys J
. 2004 Apr;
86(5):2748-57.
PMID: 15111393
Sonic hedgehog (Shh) controls critical cellular decisions between distinct fates in many systems, particularly in stem cells. The Shh network functions as a genetic switch, and we have theoretically and...
10.
Lai K, Kaspar B, Gage F, Schaffer D
Nat Neurosci
. 2002 Dec;
6(1):21-7.
PMID: 12469128
Neural stem cells exist in the developing and adult nervous systems of all mammals, but the basic mechanisms that control their behavior are not yet well understood. Here, we investigated...