Karen L Porter
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Explore the profile of Karen L Porter including associated specialties, affiliations and a list of published articles.
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9
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80
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Recent Articles
1.
Shetty G, Porter K, Zhou W, Shao S, Weng C, Meistrich M
Endocrinology
. 2011 Jul;
152(9):3504-14.
PMID: 21733828
Why both testosterone (T) suppression and cryptorchidism reverse the block in spermatogonial differentiation in adult mice homozygous for the juvenile spermatogonial depletion (jsd) mutation has been a conundrum. To resolve...
2.
Porter K, Olmstead A, Kumsher D, Dennis W, Sprando R, Holcombe G, et al.
Aquat Toxicol
. 2011 Apr;
103(3-4):159-69.
PMID: 21470552
Endocrine disrupting chemicals that activate the estrogen receptor are routinely detected in the environment and are a concern for the health of both exposed humans and indigenous wildlife. We exposed...
3.
Porter K, Shetty G, Shuttlesworth G, Weng C, Huhtaniemi I, Pakarinen P, et al.
J Androl
. 2009 Jan;
30(4):440-51.
PMID: 19136390
Irradiation of LBNF(1) rat testes induces spermatogonial differentiation arrest, which can be reversed by gonadotropin-releasing hormone (GnRH) antagonist-induced suppression of intratesticular testosterone (ITT) and follicle-stimulating hormone (FSH). Although exogenous estrogen...
4.
Knechtges P, Sprando R, Porter K, Brennan L, Miller M, Kumsher D, et al.
Environ Toxicol Chem
. 2007 Mar;
26(3):555-64.
PMID: 17373522
In 1996, the U.S. Congress mandated the development of a screening program for endocrine-disrupting chemicals (EDCs) using validated test systems. Subsequently, the Endocrine Disruptor Screening and Testing Advisory Committee recommended...
5.
Shetty G, Weng C, Porter K, Zhang Z, Pakarinen P, Kumar T, et al.
Endocrinology
. 2006 Apr;
147(7):3563-70.
PMID: 16627582
The jsd mice experience a single wave of spermatogenesis, followed by an arrest of spermatogenesis because of a block in spermatogonial differentiation. Previous pharmacological and surgical studies have indicated that...
6.
Porter K, Shetty G, Meistrich M
Endocrinology
. 2005 Nov;
147(3):1297-305.
PMID: 16306082
Irradiation of LBNF1 rat testes induces arrest of spermatogonial differentiation, which can be reversed by suppression of testosterone with GnRH antagonist treatment. The cause of the arrest is unknown. We...
7.
Meistrich M, Wilson G, Porter K, Huhtaniemi I, Shetty G, Shuttlesworth G
Toxicol Sci
. 2003 Sep;
76(2):418-26.
PMID: 14514963
The exposure of men to the nematocide dibromochloropropane (DBCP) has caused prolonged oligo- and azoospermia, which occasionally reverses spontaneously. We recently demonstrated that in testes of rats treated with a...
8.
Meistrich M, Wilson G, Shuttlesworth G, Porter K
Reprod Toxicol
. 2003 May;
17(3):263-71.
PMID: 12759094
Exposure to the nematocide dibromochloropropane (DBCP) has caused prolonged oligo- and azoospermia in men. There are questions regarding the cellular targets resulting in this effect. In this study we characterized...
9.
Porter K, Chanda S, Wang H, Gaido K, Smart R, Robinette C
Toxicol Sci
. 2002 Sep;
69(1):42-8.
PMID: 12215659
Mirex, an organochlorine pesticide, is a potent non-phorbol ester tumor promoter in mouse skin. Previous studies have shown that female mice are 3 times more sensitive to mirex tumor promotion...