Karen Kallio
Overview
Explore the profile of Karen Kallio including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
271
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0
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Recent Articles
1.
Hill J, Massaquoi M, Sweeney E, Wall E, Jahl P, Bell R, et al.
Cell Metab
. 2022 Oct;
34(11):1779-1791.e9.
PMID: 36240759
Microbiome dysbiosis is a feature of diabetes, but how microbial products influence insulin production is poorly understood. We report the mechanism of BefA, a microbiome-derived protein that increases proliferation of...
2.
Sweeney E, Perkins A, Kallio K, James Remington S, Guillemin K
Protein Sci
. 2018 Sep;
27(11):1961-1968.
PMID: 30171638
Bacteria use chemoreceptor proteins to sense and navigate their chemical environments. The most common class of chemoreceptors are transmembrane proteins that sense chemical cues through binding of a small-molecule ligand...
3.
Tang L, Wang Y, Zhu L, Kallio K, Remington S, Fang C
Phys Chem Chem Phys
. 2018 May;
20(18):12517-12526.
PMID: 29708241
Photoactivated proton transfer (PT) wire is responsible for the glow of green fluorescent protein (GFP), which is crucial for bioimaging and biomedicine. In this work, a new GFP-S65T/S205V double mutant...
4.
Chen Z, Tian Z, Kallio K, Oleson A, Ji A, Borchardt D, et al.
J Am Chem Soc
. 2016 Mar;
138(14):4900-7.
PMID: 27019313
Boronic acid and esters have been extensively utilized for molecular recognition and chemical sensing. We recently reported a genetically encoded peroxynitrite (ONOO(-))-specific fluorescent sensor, pnGFP, based on the incorporation of...
5.
Wineman-Fisher V, Simkovitch R, Shomer S, Gepshtein R, Huppert D, Saif M, et al.
Phys Chem Chem Phys
. 2014 Apr;
16(23):11196-208.
PMID: 24776960
Mutations near the fluorescing chromophore of the green fluorescent protein (GFP) have direct effects on the absorption and emission spectra. Some mutants have significant band shifts and most of the...
6.
Erez Y, Gepshtein R, Presiado I, Trujillo K, Kallio K, Remington S, et al.
J Phys Chem B
. 2011 Sep;
115(41):11776-85.
PMID: 21902228
To further explore excited state proton transfer (ESPT) pathways within green fluorescent protein (GFP), mutagenesis, X-ray crystallography, and time-resolved and steady-state optical spectroscopy were employed to create and study the...
7.
Henderson J, Gepshtein R, Heenan J, Kallio K, Huppert D, Remington S
J Am Chem Soc
. 2009 Mar;
131(12):4176-7.
PMID: 19278226
Crystal structures of the photoactivatable green fluorescent protein T203H variant (PA-GFP) have been solved in the native and photoactivated states, which under 488 nm illumination are dark and brightly fluorescent,...
8.
Shu X, Wang L, Colip L, Kallio K, Remington S
Protein Sci
. 2009 Jan;
18(2):460-6.
PMID: 19165727
mPlum is a far-red fluorescent protein with emission maximum at approximately 650 nm and was derived by directed evolution from DsRed. Two residues near the chromophore, Glu16 and Ile65, were...
9.
Shu X, Leiderman P, Gepshtein R, Smith N, Kallio K, Huppert D, et al.
Protein Sci
. 2007 Oct;
16(12):2703-10.
PMID: 17965188
Wild-type green fluorescent protein (wt-GFP) has a prominent absorbance band centered at approximately 395 nm, attributed to the neutral chromophore form. The green emission arising upon excitation of this band...
10.
Shi X, Abbyad P, Shu X, Kallio K, Kanchanawong P, Childs W, et al.
Biochemistry
. 2007 Oct;
46(43):12014-25.
PMID: 17918960
In the preceding accompanying paper [Shu, X., et al. (2007) Biochemistry 46, 12005-12013], the 1.5 A resolution crystal structure of green fluorescent protein (GFP) variant S65T/H148D is presented, and the...