Karen E Stevens
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Explore the profile of Karen E Stevens including associated specialties, affiliations and a list of published articles.
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44
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1246
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Recent Articles
1.
Gault J, Thompson J, Maharajh K, Hosokawa P, Stevens K, Olincy A, et al.
Neuromodulation
. 2020 Feb;
23(4):478-488.
PMID: 32022409
Introduction: The P50, a positive auditory-evoked potential occurring 50 msec after an auditory click, has been characterized extensively with electroencephalography (EEG) to detect aberrant auditory electrophysiology in disorders like schizophrenia...
2.
Smucny J, Stevens K, Tregellas J
NPJ Schizophr
. 2016 Jun;
1:15053.
PMID: 27336049
[This corrects the article DOI: 10.1038/npjschz.2015.2.][This corrects the article DOI: 10.1038/npjschz.2015.2.].
3.
Freund R, Graw S, Choo K, Stevens K, Leonard S, DellAcqua M
Neurosci Lett
. 2016 May;
627:1-6.
PMID: 27233215
Reduced α7 nicotinic acetylcholine receptor (nAChR) function is linked to impaired hippocampal-dependent sensory processing and learning and memory in schizophrenia. While knockout of the Chrna7 gene encoding the α7nAChR on...
4.
Tregellas J, Smucny J, Legget K, Stevens K
Schizophr Res
. 2015 Oct;
169(1-3):351-354.
PMID: 26453015
Although the ketogenic diet has shown promise in a pilot study and case report in schizophrenia, its effects in animal models of hypothesized disease mechanisms are unknown. This study examined...
5.
Smucny J, Stevens K, Tregellas J
NPJ Schizophr
. 2015 Aug;
1.
PMID: 26317115
Schizophrenia is associated with deficits in P50 gating. This deficit is preclinically modeled in the DBA/2 mouse by depth recordings in the hippocampus. Neurobiologically, the deficit may be due to...
6.
Bates R, Stith B, Stevens K
J Pharmacol Sci
. 2015 Aug;
128(4):193-201.
PMID: 26275469
Neural tissue exposure to valproic acid (VPA) increases several pro-survival phospho-proteins that can be used as biomarkers for indicating a beneficial drug response (pAkt(Ser473), pGSK3β(Ser9), pErk1/2(Thr202/Tyr204)). Unfortunately, targeting VPA to...
7.
Stevens K, Zheng L, Floyd K, Stitzel J
Brain Res
. 2015 Mar;
1611:8-17.
PMID: 25744161
Positive allosteric modulators (PAMs) for the α7 nicotinic receptor hold promise for the treatment of sensory inhibition deficits observed in schizophrenia patients. Studies of these compounds in the DBA/2 mouse,...
8.
Wu W, Adams C, Stevens K, Chow K, Freedman R, Patterson P
Brain Behav Immun
. 2015 Feb;
46:192-202.
PMID: 25683697
Mutation of human chromosome 15q13.3 increases the risk for autism and schizophrenia. One of the noteworthy genes in 15q13.3 is CHRNA7, which encodes the nicotinic acetylcholine receptor alpha 7 subunit...
9.
Schulz K, Pearson J, Gasparrini M, Brooks K, Drake-Frazier C, Zajkowski M, et al.
Behav Brain Res
. 2014 Mar;
268:104-10.
PMID: 24675162
Brain cholinergic dysfunction is associated with neuropsychiatric illnesses such as depression, anxiety, and schizophrenia. Maternal stress exposure is associated with these same illnesses in adult offspring, yet the relationship between...
10.
Stevens K, Choo K, Stitzel J, Marks M, Adams C
Brain Res
. 2014 Jan;
1552:26-33.
PMID: 24462939
Perinatal choline supplementation has produced several benefits in rodent models, from improved learning and memory to protection from the behavioral effects of fetal alcohol exposure. We have shown that supplemented...