Karen Davey
Overview
Explore the profile of Karen Davey including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
237
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0
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Recent Articles
1.
Tang J, Huang H, Muirhead R, Zhou Y, Li J, DeFelice J, et al.
Brain Commun
. 2024 Jul;
6(4):fcae218.
PMID: 39035420
Amyloid-β pathology and neurofibrillary tangles lead to glial activation and neurodegeneration in Alzheimer's disease. In this study, we investigated the relationships between the levels of amyloid-β oligomers, amyloid-β plaques, glial...
2.
Fancy N, Smith A, Caramello A, Tsartsalis S, Davey K, Muirhead R, et al.
Acta Neuropathol
. 2024 May;
147(1):78.
PMID: 38695952
Aging is associated with cell senescence and is the major risk factor for AD. We characterized premature cell senescence in postmortem brains from non-diseased controls (NDC) and donors with Alzheimer's...
3.
Monti M, Herman R, Mancini L, Capitanchik C, Davey K, Dawson C, et al.
Mol Syst Biol
. 2024 Mar;
20(5):573-589.
PMID: 38531971
Characterising RNA-protein interaction dynamics is fundamental to understand how bacteria respond to their environment. In this study, we have analysed the dynamics of 91% of the Escherichia coli expressed proteome...
4.
Tsartsalis S, Sleven H, Fancy N, Wessely F, Smith A, Willumsen N, et al.
Nat Commun
. 2024 Mar;
15(1):2243.
PMID: 38472200
Brain perfusion and blood-brain barrier (BBB) integrity are reduced early in Alzheimer's disease (AD). We performed single nucleus RNA sequencing of vascular cells isolated from AD and non-diseased control brains...
5.
Rafiee M, Rohban S, Davey K, Ule J, Luscombe N
Brain
. 2023 Feb;
146(6):2547-2556.
PMID: 36789492
Valosin-containing protein (VCP) is a hexameric ATPase associated with diverse cellular activities. Genetic mutations in VCP are associated with several forms of muscular and neuronal degeneration, including amyotrophic lateral sclerosis...
6.
Rafiee M, Zagalak J, Sidorov S, Steinhauser S, Davey K, Ule J, et al.
Nucleic Acids Res
. 2021 Dec;
49(22):13092-13107.
PMID: 34871434
RNA-binding proteins (RBPs) play diverse roles in regulating co-transcriptional RNA-processing and chromatin functions, but our knowledge of the repertoire of chromatin-associated RBPs (caRBPs) and their interactions with chromatin remains limited....
7.
Smith A, Davey K, Tsartsalis S, Khozoie C, Fancy N, Tang S, et al.
Acta Neuropathol
. 2021 Nov;
143(1):75-91.
PMID: 34767070
To better define roles that astrocytes and microglia play in Alzheimer's disease (AD), we used single-nuclei RNA-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation...
8.
Davey K, Wong D, Konopacki F, Kwa E, Ly T, Fiegler H, et al.
Sci Rep
. 2021 Apr;
11(1):7918.
PMID: 33846365
Single cell transcriptome profiling has emerged as a breakthrough technology for the high-resolution understanding of complex cellular systems. Here we report a flexible, cost-effective and user-friendly droplet-based microfluidics system, called...
9.
Ling H, Gelpi E, Davey K, Jaunmuktane Z, Mok K, Jabbari E, et al.
Acta Neuropathol
. 2020 Jan;
139(4):717-734.
PMID: 31950334
Corticobasal degeneration typically progresses gradually over 5-7 years from onset till death. Fulminant corticobasal degeneration cases with a rapidly progressive course were rarely reported (RP-CBD). This study aimed to investigate...
10.
Goldfinger M, Ling H, Tilley B, Liu A, Davey K, Holton J, et al.
Acta Neuropathol
. 2018 Nov;
136(6):973-974.
PMID: 30377771
No abstract available.