Karen Crasta
Overview
Explore the profile of Karen Crasta including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
917
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Recent Articles
1.
Glaviano A, Wander S, Baird R, Yap K, Lam H, Toi M, et al.
Drug Resist Updat
. 2024 Jun;
76:101103.
PMID: 38943828
Cell cycle dysregulation is a hallmark of cancer that promotes eccessive cell division. Cyclin-dependent kinase 4 (CDK4) and cyclin-dependent kinase 6 (CDK6) are key molecules in the G1-to-S phase cell...
2.
Elazary Y, Cheow K, Cheng R, Ghosh R, Shainer I, Wexler Y, et al.
J Pineal Res
. 2023 Jan;
74(3):e12854.
PMID: 36692235
Photoreceptors in the vertebrate eye are dependent on the retinal pigmented epithelium for a variety of functions including retinal re-isomerization and waste disposal. The light-sensitive pineal gland of fish, birds,...
3.
Srinivas U, Tay N, Jaynes P, Anbuselvan A, Ramachandran G, Wardyn J, et al.
Oncogene
. 2022 May;
41(24):3382.
PMID: 35523948
No abstract available.
4.
Srinivas U, Tay N, Jaynes P, Anbuselvan A, Ramachandran G, Wardyn J, et al.
Oncogene
. 2022 Mar;
41(13):1986-2002.
PMID: 35236967
Inhibitors of the mitotic kinase PLK1 yield objective responses in a subset of refractory cancers. However, PLK1 overexpression in cancer does not correlate with drug sensitivity, and the clinical development...
5.
Breaking the vicious circle: Extrachromosomal circular DNA as an emerging player in tumour evolution
Robert M, Crasta K
Semin Cell Dev Biol
. 2021 Dec;
123:140-150.
PMID: 34857471
Extrachromosomal circular DNA (ecDNA) or double minutes have gained renewed interest since its discovery more than five decades ago, emerging as potent drivers of tumour evolution. This has largely been...
6.
7.
Jakhar R, Crasta K
Int J Mol Sci
. 2019 May;
20(10).
PMID: 31137607
Communication between cells is quintessential for biological function and cellular homeostasis. Membrane-bound extracellular vesicles known as exosomes play pivotal roles in mediating intercellular communication in tumor microenvironments. These vesicles and...
8.
Wong A, Chen S, Yang L, Kanagasundaram Y, Crasta K
Cell Death Discov
. 2018 Dec;
4:109.
PMID: 30510774
Aberrant lipid accumulation is a hallmark of cancer known to contribute to its aggressiveness and malignancy. Emerging studies have demonstrated context-dependent changes in lipid metabolism during chemotherapy. However, there is...
9.
Shyu Jr P, Wong X, Crasta K, Thibault G
Biosci Rep
. 2018 Aug;
38(5).
PMID: 30111611
Lipid droplets (LD) have increasingly become a major topic of research in recent years following its establishment as a highly dynamic organelle. Contrary to the initial view of LDs being...
10.
Crasta K, Aneja R
Endocr Relat Cancer
. 2017 Aug;
24(9):E3-E5.
PMID: 28808042
No abstract available.