Kara Wolfe
Overview
Explore the profile of Kara Wolfe including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
163
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0
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Recent Articles
1.
Kofuji S, Wolfe K, Sumita K, Kageyama S, Yoshino H, Hirota Y, et al.
Biochem Biophys Res Commun
. 2024 May;
718:149981.
PMID: 38735134
In animal cells, vacuoles are absent, but can be induced by diseases and drugs. While phosphoinositides are critical for membrane trafficking, their role in the formation of these vacuoles remains...
2.
Wolfe K, Kamata R, Coutinho K, Inoue T, Sasaki A
Front Oncol
. 2020 Nov;
10:554272.
PMID: 33224873
Despite advances in targeted therapeutics and understanding in molecular mechanisms, metastasis remains a substantial obstacle for cancer treatment. Acquired genetic mutations and transcriptional changes can promote the spread of primary...
3.
Yoshino H, Yin G, Kawaguchi R, Popov K, Temple B, Sasaki M, et al.
PLoS One
. 2019 Oct;
14(10):e0224443.
PMID: 31639175
[This corrects the article DOI: 10.1371/journal.pone.0219436.].
4.
Naffouje R, Grover P, Yu H, Sendilnathan A, Wolfe K, Majd N, et al.
Cancers (Basel)
. 2019 Sep;
11(9).
PMID: 31514446
The purine nucleotides ATP and GTP are essential precursors to DNA and RNA synthesis and fundamental for energy metabolism. Although de novo purine nucleotide biosynthesis is increased in highly proliferating...
5.
Yoshino H, Yin G, Kawaguchi R, Popov K, Temple B, Sasaki M, et al.
PLoS One
. 2019 Aug;
14(8):e0219436.
PMID: 31390367
RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown that the activation state of RAS...
6.
Kofuji S, Hirayama A, Eberhardt A, Kawaguchi R, Sugiura Y, Sampetrean O, et al.
Nat Cell Biol
. 2019 Aug;
21(8):1003-1014.
PMID: 31371825
In many cancers, high proliferation rates correlate with elevation of rRNA and tRNA levels, and nucleolar hypertrophy. However, the underlying mechanisms linking increased nucleolar transcription and tumorigenesis are only minimally...
7.
Wolfe K, Kofuji S, Yoshino H, Sasaki M, Okumura K, Sasaki A
Biochem Biophys Res Commun
. 2019 Jun;
516(1):50-56.
PMID: 31196624
Compartmentalization is vital for biological systems at multiple levels, including biochemical reactions in metabolism. Organelle-based compartments such as mitochondria and peroxisomes sequester the responsible enzymes and increase the efficiency of...