Kara Hunter
Overview
Explore the profile of Kara Hunter including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
447
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Recent Articles
1.
Romero-Perez P, Moran H, Horani A, Truong A, Manriquez-Sandoval E, Ramirez J, et al.
bioRxiv
. 2024 Aug;
PMID: 39131385
Cellular desiccation - the loss of nearly all water from the cell - is a recurring stress in an increasing number of ecosystems that can drive protein unfolding and aggregation....
2.
Hunter K, Rainbow D, Plagnol V, Todd J, Peterson L, Wicker L
J Immunol
. 2007 Dec;
179(12):8341-9.
PMID: 18056379
Two loci, Idd5.1 and Idd5.2, that determine susceptibility to type 1 diabetes (T1D) in the NOD mouse are on chromosome 1. Idd5.1 is likely accounted for by a synonymous single...
3.
Hamilton-Williams E, Martinez X, Lyman M, Hunter K, Wicker L, Sherman L
Ann N Y Acad Sci
. 2007 Mar;
1103:118-27.
PMID: 17376833
Type 1 diabetes (T1D) occurs because of lack of T cell tolerance to islet antigens. We hypothesized that critical genetic susceptibility loci that control progression to T1D, designated as insulin-dependent...
4.
Yamanouchi J, Rainbow D, Serra P, Howlett S, Hunter K, Garner V, et al.
Nat Genet
. 2007 Feb;
39(3):329-37.
PMID: 17277778
Autoimmune diseases are thought to result from imbalances in normal immune physiology and regulation. Here, we show that autoimmune disease susceptibility and resistance alleles on mouse chromosome 3 (Idd3) correlate...
5.
Silveira P, Chapman H, Stolp J, Johnson E, Cox S, Hunter K, et al.
J Immunol
. 2006 Nov;
177(10):7033-41.
PMID: 17082619
Autoreactive T cells clearly mediate the pancreatic beta cell destruction causing type 1 diabetes (T1D). However, studies in NOD mice indicate that B cells also contribute to pathogenesis because their...
6.
Chamberlain G, Wallberg M, Rainbow D, Hunter K, Wicker L, Green E
J Immunol
. 2006 Oct;
177(8):5105-14.
PMID: 17015694
Identification of candidate genes and their immunological mechanisms that control autoaggressive T cells in inflamed environments, may lead to novel therapies for autoimmune diseases, like type 1 diabetes (T1D). In...
7.
Kissler S, Stern P, Takahashi K, Hunter K, Peterson L, Wicker L
Nat Genet
. 2006 Mar;
38(4):479-83.
PMID: 16550170
Type 1 diabetes is an autoimmune disease influenced by multiple genetic loci. Although more than 20 insulin-dependent diabetes (Idd) loci have been implicated in the nonobese diabetic (NOD) mouse model,...
8.
Wicker L, Clark J, Fraser H, Garner V, Gonzalez-Munoz A, Healy B, et al.
J Autoimmun
. 2005 Nov;
25 Suppl:29-33.
PMID: 16257508
The identification of causative genes for the autoimmune disease type 1 diabetes (T1D) in humans and candidate genes in the NOD mouse has made significant progress in recent years. In...
9.
Martinez X, Kreuwel H, Redmond W, Trenney R, Hunter K, Rosen H, et al.
J Immunol
. 2005 Jul;
175(3):1677-85.
PMID: 16034108
Although candidate genes controlling autoimmune disease can now be identified, a major challenge that remains is defining the resulting cellular events mediated by each locus. In the current study we...
10.
Wicker L, Moule C, Fraser H, Penha-Goncalves C, Rainbow D, Garner V, et al.
Novartis Found Symp
. 2005 Jul;
267:57-65.
PMID: 15999801
The understanding of the genetic basis of type 1 diabetes and other autoimmune diseases and the application of that knowledge to their treatment, cure and eventual prevention has been a...