Kanglong Wang
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Explore the profile of Kanglong Wang including associated specialties, affiliations and a list of published articles.
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10
Citations
83
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Recent Articles
1.
Jiang J, Gao Y, Wang J, Huang Y, Yang R, Zhang Y, et al.
Cell Metab
. 2025 Feb;
PMID: 40015281
Metabolic-dysfunction-associated steatohepatitis (MASH) remains a major health challenge. Herein, we identify sphingomyelin phosphodiesterase 3 (SMPD3) as a key driver of hepatic ceramide accumulation through increasing sphingomyelin hydrolysis at the cell...
2.
Wang Y, Sun C, Cao Y, Jiao T, Wang K, Li J, et al.
J Ethnopharmacol
. 2024 Nov;
338(Pt 1):119025.
PMID: 39489360
Ethnopharmacological Relevance: Ulcerative colitis (UC), a chronic inflammatory bowel disease, has become a significant public health challenge due to the limited effectiveness of available therapies. Huoxiang Zhengqi (HXZQ), a well-established...
3.
Guo X, Wang J, Xu H, Wang Y, Cao Y, Wen Y, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Nov;
1869(1):159419.
PMID: 37951383
The disruption of the diurnal rhythm has been recognized as a significant contributing factor to metabolic dysregulation. The important role of gut microbiota and bile acid metabolism has attracted extensive...
4.
Wang J, Guo X, Zou Z, Yu M, Li X, Xu H, et al.
Biomed Pharmacother
. 2023 Sep;
166:115434.
PMID: 37677965
Renal interstitial fibrosis (RIF), a progressive process affecting the kidneys in chronic kidney disease (CKD), currently lacks an effective therapeutic intervention. Traditional Chinese medicine (TCM) has shown promise in reducing...
5.
Liu Y, Zhong X, Lin S, Xu H, Liang X, Wang Y, et al.
Microbiome
. 2023 Aug;
11(1):182.
PMID: 37580786
No abstract available.
6.
Xu H, Wang J, Liu Y, Wang Y, Zhong X, Li C, et al.
Anal Chim Acta
. 2023 Mar;
1251:341039.
PMID: 36925303
The gut microbiota interacts with the host via production of various metabolites of dietary nutrients. Herein, we proposed the concept of the gut microbiota-derived core nutrient metabolome, which covers 43...
7.
Liu Y, Zhong X, Lin S, Xu H, Liang X, Wang Y, et al.
Microbiome
. 2022 Dec;
10(1):226.
PMID: 36517893
Objective: High intake of caffeoylquinic acid (CQA)-rich dietary supplements, such as green coffee bean extracts, offers health-promoting effects on maintaining metabolic homeostasis. Similar to many active herbal ingredients with high...
8.
Zhang C, Liu Y, Wang Y, Ge X, Jiao T, Yin J, et al.
J Med Chem
. 2022 Sep;
65(19):13452-13472.
PMID: 36107013
Farnesoid X receptor (FXR) has emerged as a promising therapeutic target for nonalcoholic steatohepatitis (NASH) because of its tightly interwoven relationship with bile acid homeostasis, inflammation, fibrosis, and glucose and...
9.
Chen L, Jiao T, Liu W, Luo Y, Wang J, Guo X, et al.
Cell Stem Cell
. 2022 Sep;
29(9):1366-1381.e9.
PMID: 36055192
Although disrupted bile acid (BA) homeostasis is implicated in inflammatory bowel disease (IBD), the role of hepatic BA metabolism in the pathogenesis of colitis is poorly understood. Here, we found...
10.
Zhao J, Xie C, Wang K, Takahashi S, Krausz K, Lu D, et al.
Toxicol Lett
. 2020 Aug;
333:290-302.
PMID: 32835833
Triptolide, a major active component of Triptergium wilfordii Hook. f, is used in the treatment of autoimmune disease. However, triptolide is associated with severe adverse reactions, especially hepatotoxicity, which limits...