Kamlesh Gidwani
Overview
Explore the profile of Kamlesh Gidwani including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
893
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Recent Articles
1.
Afshari A, Chang V, Thomsson K, Hoglund J, Browne E, Karadzhov G, et al.
Mol Cell Proteomics
. 2025 Feb;
24(3):100923.
PMID: 39922311
Lubricin/proteoglycan-4 (PRG-4) is a mucinous glycoprotein that lubricates cartilage and maintains normal tissue function and cell homeostasis. Altered O-glycoproteforms of lubricin have been found in osteoarthritis (OA) synovial fluid (SF),...
2.
Ruma S, Vinod R, Jain S, Huhtinen K, Hynninen J, Leivo J, et al.
Sci Rep
. 2025 Jan;
15(1):3171.
PMID: 39863644
Glycosylation changes of circulating proteins carrying the CA19-9 antigen may offer new targets for detection methods to be explored for the diagnosis of epithelial ovarian cancer (EOC). Search for assay...
3.
Verhassel A, Kimani M, Gidwani K, Sandholm J, Gawlitza K, Rurack K, et al.
Nanomedicine (Lond)
. 2024 Oct;
19(29):2463-2478.
PMID: 39382009
Fluorescence detection of breast and prostate cancer cells expressing Tn-antigen, a tumor marker, with lectin (VVL)-labeled nanoparticles. Breast and prostate cancer cells engineered to express high levels of Tn-antigen and...
4.
Islam M, Dhondt B, Syed P, Khan M, Gidwani K, Webber J, et al.
J Extracell Biol
. 2024 Jun;
1(10):e64.
PMID: 38939212
Urinary extracellular vesicles (uEVs) are enriched with glycosylated proteins which have been extensively studied as putative biomarkers of urological cancers. Here, we characterized the glycosylation and integrin profile of EVs...
5.
Ekman M, Salminen T, Raiko K, Soukka T, Gidwani K, Martiskainen I
Anal Bioanal Chem
. 2024 Apr;
416(13):3251-3260.
PMID: 38584178
Multiplexed lateral flow assays (LFAs) offer efficient on-site testing by simultaneously detecting multiple biomarkers from a single sample, reducing costs. In cancer diagnostics, where biomarkers can lack specificity, multiparameter detection...
6.
Islam M, Khan M, Gidwani K, Witwer K, Lamminmaki U, Leivo J
Biomark Res
. 2023 Sep;
11(1):85.
PMID: 37773167
Extracellular vesicles (EVs) have considerable potential as diagnostic, prognostic, and therapeutic agents, in large part because molecular patterns on the EV surface betray the cell of origin and may also...
7.
Jain S, Parimelazhagan Santhi P, Vinod R, Ruma S, Huhtinen K, Pettersson K, et al.
Clin Chim Acta
. 2023 Apr;
543:117323.
PMID: 37003518
Background: Glycans are strongly involved in stability and function of integrins (ITG) and tetraspanin protein CD63 and their respective interaction partners as they are dysregulated in the tumorigenic processes. Glycosylation...
8.
Diagnostic potential of nanoparticle aided assays for MUC16 and MUC1 glycovariants in ovarian cancer
Jain S, Nadeem N, Ulfenborg B, Makela M, Ruma S, Terava J, et al.
Int J Cancer
. 2022 May;
151(7):1175-1184.
PMID: 35531590
Our study reports the discovery and evaluation of nanoparticle aided sensitive assays for glycovariants of MUC16 and MUC1 in a unique collection of paired ovarian cyst fluids and serum samples...
9.
Vinod R, Mahran R, Routila E, Leivo J, Pettersson K, Gidwani K
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638669
Extracellular vesicles (EVs) are found in all biological fluids, providing potential for the identification of disease biomarkers such as colorectal cancer (CRC). EVs are heavily glycosylated with specific glycoconjugates such...
10.
Terava J, Verhassel A, Botti O, Islam M, Leivo J, Wittfooth S, et al.
Cancer Rep (Hoboken)
. 2021 Aug;
5(8):e1540.
PMID: 34423573
Background: Breast cancer is a very common cancer that can be severe if not discovered early. The current tools to detect breast cancer need improvement. Cancer has a universal tendency...