Kaitlin N Allen
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Explore the profile of Kaitlin N Allen including associated specialties, affiliations and a list of published articles.
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13
Citations
87
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Recent Articles
1.
Allen K, Torres-Velarde J, Vazquez J, Moreno-Santillan D, Sudmant P, Vazquez-Medina J
BMC Biol
. 2024 Apr;
22(1):91.
PMID: 38654271
Background: Elephant seals exhibit extreme hypoxemic tolerance derived from repetitive hypoxia/reoxygenation episodes they experience during diving bouts. Real-time assessment of the molecular changes underlying protection against hypoxic injury in seals...
2.
Torres-Velarde J, Allen K, Salvador-Pascual A, Leija R, Luong D, Moreno-Santillan D, et al.
Free Radic Biol Med
. 2024 Apr;
218:82-93.
PMID: 38579937
Peroxiredoxin 6 (Prdx6) repairs peroxidized membranes by reducing oxidized phospholipids, and by replacing oxidized sn-2 fatty acyl groups through hydrolysis/reacylation by its phospholipase A (aiPLA) and lysophosphatidylcholine acyltransferase activities. Prdx6...
3.
Allen K, Torres-Velarde J, Vazquez J, Moreno-Santillan D, Sudmant P, Vazquez-Medina J
bioRxiv
. 2023 Jul;
PMID: 37461722
Elephant seals experience extreme hypoxemia during diving bouts. Similar depletions in oxygen availability characterize pathologies including myocardial infarction and ischemic stroke in humans, but seals manage these repeated episodes without...
4.
Noh H, Turner-Maier J, Schulberg S, Fitzgerald M, Johnson J, Allen K, et al.
Commun Biol
. 2022 Feb;
5(1):140.
PMID: 35177770
The Weddell seal (Leptonychotes weddellii) thrives in its extreme Antarctic environment. We generated the Weddell seal genome assembly and a high-quality annotation to investigate genome-wide evolutionary pressures that underlie its...
5.
Ensminger D, Crocker D, Lam E, Allen K, Vazquez-Medina J
J Exp Biol
. 2021 Sep;
224(18).
PMID: 34524449
The hypothalamic-pituitary-adrenal (HPA) axis controls the release of glucocorticoids, which regulate immune and inflammatory function by modulating cytokines, white blood cells and oxidative stress via glucocorticoid receptor (GR) signaling. Although...
6.
Akther F, Razan M, Shaligram S, Graham J, Stanhope K, Allen K, et al.
Front Physiol
. 2021 Aug;
12:616317.
PMID: 34366875
Previous reports suggest that diabetes may differentially affect the vascular beds of females and males. The objectives of this study were to examine whether there were (1) sex differences in...
7.
Ensminger D, Salvador-Pascual A, Arango B, Allen K, Vazquez-Medina J
Comp Biochem Physiol A Mol Integr Physiol
. 2021 Mar;
256:110929.
PMID: 33647461
Fasting is a component of many species' life history due to environmental factors or behavioral patterns that limit access to food. Despite metabolic and physiological challenges associated with these life...
8.
Lam E, Allen K, Torres-Velarde J, Vazquez-Medina J
Integr Comp Biol
. 2020 Jun;
60(2):348-360.
PMID: 32516367
Marine mammals exhibit some of the most dramatic physiological adaptations in their clade and offer unparalleled insights into the mechanisms driving convergent evolution on relatively short time scales. Some of...
9.
Allen K, Vazquez-Medina J
Front Physiol
. 2019 Oct;
10:1199.
PMID: 31620019
Reperfusion injury follows ischemia/reperfusion events occurring during myocardial infarction, stroke, embolism, and other peripheral vascular diseases. Decreased blood flow and reduced oxygen tension during ischemic episodes activate cellular pathways that...
10.
Allen K, Vazquez-Medina J, Lawler J, Mellish J, Horning M, G Hindle A
J Exp Biol
. 2019 Jun;
222(Pt 12).
PMID: 31171605
Seals experience repeated bouts of ischemia-reperfusion while diving, potentially exposing their tissues to increased oxidant generation and thus oxidative damage and accelerated aging. We contrasted markers of oxidative damage with...