Kai Diederich
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Explore the profile of Kai Diederich including associated specialties, affiliations and a list of published articles.
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43
Citations
675
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Recent Articles
1.
Ghrelin promotes neurologic recovery and neurogenesis in the chronic phase after experimental stroke
Beuker C, Schreiner U, Strecker J, Altach E, Ratzel V, Schmidt-Pogoda A, et al.
Neurol Res Pract
. 2025 Mar;
7(1):14.
PMID: 40025613
Background: The neuroprotective and proangiogenic potential of ghrelin in acute ischemic stroke has been demonstrated in experimental studies. However, the transferability of these results is limited as ghrelin was administered...
2.
Diederich K, Steinfath M, Bannach-Brown A, Bert B, Butzke D, Wildner P, et al.
F1000Res
. 2025 Jan;
13():858.
PMID: 39839731
The translation of animal-based biomedical research into clinical research is often inadequate. Maximizing translation should be central to animal research on human diseases, guiding researchers in study design and animal...
3.
Drude N, Diederich K, Duerr C, Haase N, Harms C, Heppner F, et al.
J Vis Exp
. 2025 Jan;
(214).
PMID: 39760355
The use of laboratory mice with a natural microbiome, such as "Wildling mice", offers a promising research tool for both basic and applied science due to their close resemblance to...
4.
Hohlbaum K, Andresen N, Mieske P, Kahnau P, Lang B, Diederich K, et al.
Open Res Eur
. 2024 Sep;
4:108.
PMID: 39257918
Background: Due to the lack of complexity and variety of stimuli, conventional housing conditions of laboratory mice do not allow these animals to fully express their behavioral repertoire, including manipulative...
5.
Strecker J, Schmidt-Pogoda A, Diederich K, Zaremba D, Wieters F, Beuker C, et al.
Brain Pathol
. 2024 Jul;
35(1):e13280.
PMID: 38946137
Demyelination of corticospinal tract neurons contributes to long-term disability after cortical stroke. Nonetheless, poststroke myelin loss has not been addressed as a therapeutic target, so far. We hypothesized that an...
6.
Kahnau P, Mieske P, Wilzopolski J, Kalliokoski O, Mandillo S, Holter S, et al.
BMC Biol
. 2023 Nov;
21(1):256.
PMID: 37953247
Background: Traditionally, in biomedical animal research, laboratory rodents are individually examined in test apparatuses outside of their home cages at selected time points. However, the outcome of such tests can...
7.
Lang B, Kahnau P, Hohlbaum K, Mieske P, Andresen N, Boon M, et al.
Front Behav Neurosci
. 2023 Oct;
17:1230082.
PMID: 37809039
The mechanisms underlying the formation and retrieval of memories are still an active area of research and discussion. Manifold models have been proposed and refined over the years, with most...
8.
Kahnau P, Jaap A, Urmersbach B, Diederich K, Lewejohann L
Open Res Eur
. 2023 Oct;
2:128.
PMID: 37799631
The cognitive bias test is used to measure the emotional state of animals with regard to future expectations. Thus, the test offers a unique possibility to assess animal welfare with...
9.
Neves M, Klippert A, Knospel F, Rudeck J, Stolz A, Ban Z, et al.
J Biomed Semantics
. 2023 Sep;
14(1):13.
PMID: 37658458
Current animal protection laws require replacement of animal experiments with alternative methods, whenever such methods are suitable to reach the intended scientific objective. However, searching for alternative methods in the...
10.
Mieske P, Scheinpflug J, Yorgan T, Brylka L, Palme R, Hobbiesiefken U, et al.
Lab Anim Res
. 2023 May;
39(1):9.
PMID: 37189184
Background: Enrichment of home cages in laboratory experiments offers clear advantages, but has been criticized in some respects. First, there is a lack of definition, which makes methodological uniformity difficult....