K W Michael Siu
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Explore the profile of K W Michael Siu including associated specialties, affiliations and a list of published articles.
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144
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2242
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Recent Articles
11.
Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen Z, Tucholska M, et al.
Clin Proteomics
. 2019 Jan;
15:41.
PMID: 30598658
Background: It may be possible to discover new diagnostic or therapeutic peptides or proteins from blood plasma by using liquid chromatography and tandem mass spectrometry to identify, quantify and compare...
12.
Grane-Boladeras N, Williams D, Tarmakova Z, Stevanovic K, Villani L, Mehrabi P, et al.
FASEB J
. 2018 Dec;
33(3):3841-3850.
PMID: 30521377
Equilibrative nucleoside transporters (ENTs) translocate nucleosides and nucleobases across plasma membranes, as well as a variety of anti-cancer, -viral, and -parasite nucleoside analogs. They are also key members of the...
13.
Lam K, Lau J, Lai C, Chu I, Martens J, Berden G, et al.
Phys Chem Chem Phys
. 2018 Jun;
20(27):18688-18698.
PMID: 29956702
Collision-induced dissociation of isotopically labelled protonated pentaglycine produced two abundant [b5]+ ions, the products of the loss of water from the first and second amide groups, labelled [b5]+I and [b5]+II....
14.
Lam K, Lau J, Lai C, Hopkinson A, Siu K
J Phys Chem B
. 2017 Sep;
121(41):9541-9547.
PMID: 28945091
Collision-induced dissociations of isotopically labeled protonated tetraglycines establish that the [b] ion formed by loss of water from the second amide bond (structure II) rearranges to form N-protonated 3,5-dihydro-4H-imidazol-4-one (structure...
15.
Mu X, Lau J, Lai C, Siu K, Hopkinson A, Chu I
Phys Chem Chem Phys
. 2017 Jun;
19(25):16923-16933.
PMID: 28631796
Four isomers of the radical cation of tripeptide phenylalanylglycyltryptophan, in which the initial location of the radical center is well defined, have been isolated and their collision-induced dissociation (CID) spectra...
16.
Law H, Szeto S, Quan Q, Zhao Y, Zhang Z, Krakovska O, et al.
J Proteome Res
. 2017 Jan;
16(3):1150-1166.
PMID: 28102082
Stroke is one of the main causes of mortality and long-term disability worldwide. The pathophysiological mechanisms underlying this disease are not well understood, particularly in the chronic phase after the...
17.
Lau J, Zhao J, Williams D, Wu B, Wang Y, Madler S, et al.
Phys Chem Chem Phys
. 2016 Jun;
18(27):18119-27.
PMID: 27327880
Macrocyclization is commonly observed in large bn(+) (n≥ 4) ions and as a consequence can lead to incorrect protein identification due to sequence scrambling. In this work, the analogous [b5-...
18.
Mu X, Lau J, Lai C, Siu K, Hopkinson A, Chu I
Phys Chem Chem Phys
. 2016 Apr;
18(16):11168-75.
PMID: 27048940
Peptide radical cations that contain an aromatic amino acid residue cleave to give [zn - H]˙⁺ ions with [b2 - H - 17]˙⁺ and [c1 - 17](+) ions, the dominant...
19.
Matta A, Masui O, Siu K, Ralhan R
Proteomics
. 2016 Feb;
16(7):1079-89.
PMID: 26857332
Advancements in genomics, proteomics, and bioinformatics have improved our understanding of gene/protein networks involved in intra- and intercellular communication and tumor-host interactions. Using proteomics integrated with bioinformatics, previously we reported...
20.
Butler M, Siu K, Hopkinson A
Phys Chem Chem Phys
. 2016 Feb;
18(8):6047-52.
PMID: 26841083
The fragmentation pathways of protonated mono- and di-nitrosylated derivatives from the dipeptide Cys-Cys obtained by electrospray were examined. Protonated mononitrosylated dipeptide upon loss of ˙NO formed a radical cation, which...