K Vleminckx
Overview
Explore the profile of K Vleminckx including associated specialties, affiliations and a list of published articles.
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20
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1109
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Recent Articles
1.
Song J, Feng Y, Acke F, Coucke P, Vleminckx K, Dhooge I
Clin Genet
. 2015 Jun;
89(4):416-425.
PMID: 26100139
Waardenburg syndrome (WS) is a rare genetic disorder characterized by hearing loss (HL) and pigment disturbances of hair, skin and iris. Classifications exist based on phenotype and genotype. The auditory...
2.
de Groote P, Tran H, Fransen M, Tanghe G, Urwyler C, De Craene B, et al.
Cell Death Differ
. 2014 Nov;
22(6):1012-24.
PMID: 25430793
Receptor-interacting protein kinase 4 (RIPK4)-deficient mice have epidermal defects and fusion of all external orifices. These are similar to Bartsocas-Papas syndrome and popliteal pterygium syndrome (PPS) in humans, for which...
3.
De Schamphelaere K, Stubblefield W, Rodriguez P, Vleminckx K, Janssen C
Sci Total Environ
. 2010 Sep;
408(22):5362-71.
PMID: 20813395
The European Union regulation on Registration, Evaluation, Authorization and Restriction of Chemical substances (REACH) (EC, 2006) requires the characterization of the chronic toxicity of many chemicals in the aquatic environment,...
4.
Hecht A, Vleminckx K, Stemmler M, VAN Roy F, Kemler R
EMBO J
. 2000 Apr;
19(8):1839-50.
PMID: 10775268
Wnt growth factors regulate a variety of developmental processes by altering specific gene expression patterns. In vertebrates beta-catenin acts as transcriptional activator, which is needed to overcome target gene repression...
5.
Vleminckx K, Kemler R
Bioessays
. 1999 May;
21(3):211-20.
PMID: 10333730
Cadherins and other cell-substrate and cell-cell adhesion molecules play an essential role during development. Through their cytoplasmic interaction with the cytoskeleton, cell adhesion molecules physically link cells with the extracellular...
6.
Vleminckx K, Kemler R, Hecht A
Mech Dev
. 1999 May;
81(1-2):65-74.
PMID: 10330485
Beta-catenin is a multifunctional protein involved in cell adhesion and communication. In response to signaling by Wnt growth factors, beta-catenin associates with nuclear TCF factors to activate target genes. A...
7.
Vleminckx K, Wong E, Guger K, Rubinfeld B, Polakis P, Gumbiner B
J Cell Biol
. 1997 Jan;
136(2):411-20.
PMID: 9015311
Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene are linked to both familial and sporadic human colon cancer. So far, a clear biological function for the APC gene...
8.
Leppa S, Vleminckx K, VAN Roy F, Jalkanen M
J Cell Sci
. 1996 Jun;
109 ( Pt 6):1393-403.
PMID: 8799827
E-cadherin is a Ca(2+)-dependent cell-cell adhesion molecule, which is mainly expressed in epithelial cells. Recent studies have shown that E-cadherin has an important role as an invasion suppressor molecule in...
9.
Van den Broecke C, Vleminckx K, De Bruyne G, Van Hoorde L, Vakaet L, VAN Roy F, et al.
Clin Exp Metastasis
. 1996 May;
14(3):282-96.
PMID: 8674283
Transition from an epithelioid (e-) to a fibroblastic (f-) morphotype marks invasiveness in clinical and experimental cancer. To understand better the factors influencing such transitions, we have subcloned and manipulated...
10.
Vandenbossche G, De Bruyne G, Bruyneel E, Clemminck G, Vleminckx K, van Roy F, et al.
Int J Cancer
. 1994 Apr;
57(1):73-80.
PMID: 7512077
The invasion-suppressor molecule E-cadherin mediates Ca(2+)-dependent cell aggregation and prevents invasion. E-cadherin-positive Madin-Darby canine kidney (MDCK) cells that were non-invasive in vitro formed, upon i.p. injection, tumors that were invasive....